SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2c0d THIOREDOXIN
PEROXIDASE 2
(Plasmodium
falciparum) 		4 / 7 ILE A  41
GLY A  33
PHE A  48
LEU A  89
 None
 0.75A 3v7pA-2c0dA:
undetectable		 3v7pA-2c0dA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2c0d THIOREDOXIN
PEROXIDASE 2
(Plasmodium
falciparum) 		4 / 8 ILE A 146
ARG A 154
PRO A 188
VAL A 180
 None
 1.21A 4f4dB-2c0dA:
undetectable		 4f4dB-2c0dA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 2c0d THIOREDOXIN
PEROXIDASE 2
(Plasmodium
falciparum) 		4 / 5 PHE A  74
ASP A  80
PHE A  81
VAL A 170
 None
 0.91A 5a1rA-2c0dA:
undetectable		 5a1rA-2c0dA:
18.61