SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c1o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2c1o IGK-C PROTEIN
(Mus
musculus) 		4 / 6 LEU A 179
ALA A 130
HIS A 189
ASP A 151
 None
 1.35A 2dpzA-2c1oA:
undetectable		 2dpzA-2c1oA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2c1o IGK-C PROTEIN
(Mus
musculus) 		5 / 12 LEU A  37
LEU A  47
VAL A  78
LEU A 104
THR A 102
 None
 1.36A 2q7kA-2c1oA:
undetectable		 2q7kA-2c1oA:
22.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2c1o IGK-C PROTEIN
(Mus
musculus) 		4 / 5 TYR A 173
GLN A 166
ILE A  15
LEU A 106
 None
 1.16A 3ls4L-2c1oA:
25.5		 3ls4L-2c1oA:
67.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2c1o IGK-C PROTEIN
(Mus
musculus) 		4 / 6 ARG A  39
PHE A  62
PRO A  59
LEU A  47
 None
 1.21A 3tgvD-2c1oA:
undetectable		 3tgvD-2c1oA:
17.70