SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 2c1q BIOTIN BINDING
PROTEIN A
(Gallus
gallus) 		6 / 7 ASN A  12
LEU A  14
SER A  16
TYR A  33
THR A  35
VAL A  37
 BTN  A1126 (-3.3A)
BTN  A1126 (-4.8A)
BTN  A1126 (-2.6A)
BTN  A1126 (-4.5A)
BTN  A1126 (-3.6A)
None
 0.29A 2uz2A-2c1qA:
20.1		 2uz2A-2c1qA:
49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 2c1q BIOTIN BINDING
PROTEIN A
(Gallus
gallus) 		5 / 7 ASN A 119
LEU A  14
TYR A  33
THR A  35
VAL A  37
 BTN  A1126 (-3.2A)
BTN  A1126 (-4.8A)
BTN  A1126 (-4.5A)
BTN  A1126 (-3.6A)
None
 1.17A 2uz2A-2c1qA:
20.1		 2uz2A-2c1qA:
49.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2c1q BIOTIN BINDING
PROTEIN A
(Gallus
gallus) 		5 / 11 PHE A  80
PHE A 121
SER A  16
TYR A  33
VAL A 116
 BTN  A1126 ( 4.8A)
None
BTN  A1126 (-2.6A)
BTN  A1126 (-4.5A)
None
 1.42A 3u9fA-2c1qA:
0.0
3u9fC-2c1qA:
0.0		 3u9fA-2c1qA:
21.31
3u9fC-2c1qA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2c1q BIOTIN BINDING
PROTEIN A
(Gallus
gallus) 		5 / 12 PHE A  80
PHE A 121
SER A  16
TYR A  33
VAL A 116
 BTN  A1126 ( 4.8A)
None
BTN  A1126 (-2.6A)
BTN  A1126 (-4.5A)
None
 1.37A 3u9fP-2c1qA:
undetectable
3u9fS-2c1qA:
undetectable		 3u9fP-2c1qA:
21.31
3u9fS-2c1qA:
21.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LUR_A_STRA201_1
(AVIDIN)		 2c1q BIOTIN BINDING
PROTEIN A
(Gallus
gallus) 		7 / 10 TYR A  33
TRP A  71
PHE A  73
THR A  78
PHE A  80
TRP A  98
ASN A 119
 BTN  A1126 (-4.5A)
BTN  A1126 (-3.6A)
BTN  A1126 ( 4.9A)
BTN  A1126 (-3.4A)
BTN  A1126 ( 4.8A)
BTN  A1126 (-3.3A)
BTN  A1126 (-3.2A)
 0.40A 5lurA-2c1qA:
18.2		 5lurA-2c1qA:
53.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LUR_B_STRB201_1
(AVIDIN)		 2c1q BIOTIN BINDING
PROTEIN A
(Gallus
gallus) 		7 / 11 TYR A  33
TRP A  71
PHE A  73
THR A  78
PHE A  80
TRP A  98
ASN A 119
 BTN  A1126 (-4.5A)
BTN  A1126 (-3.6A)
BTN  A1126 ( 4.9A)
BTN  A1126 (-3.4A)
BTN  A1126 ( 4.8A)
BTN  A1126 (-3.3A)
BTN  A1126 (-3.2A)
 0.37A 5lurB-2c1qA:
17.9		 5lurB-2c1qA:
53.03