SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 2c2v STIP1 HOMOLOGY AND U
BOX-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 HIS S 261
GLY S 266
GLU S 279
LEU S 276
PRO S 248
 None
 1.31A 1mj2A-2c2vS:
undetectable
1mj2B-2c2vS:
undetectable		 1mj2A-2c2vS:
25.00
1mj2B-2c2vS:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 2c2v STIP1 HOMOLOGY AND U
BOX-CONTAINING
PROTEIN 1
(Mus
musculus) 		3 / 3 TYR S 253
VAL S 271
THR S 252
 None
 0.88A 2ygnA-2c2vS:
undetectable		 2ygnA-2c2vS:
17.65