SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c34'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.80A 1a7yA-2c34A:
undetectable		 1a7yA-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  32
PRO A  30
THR A  31
 None
 0.82A 1i3wE-2c34A:
undetectable		 1i3wE-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.86A 1i3wE-2c34A:
undetectable		 1i3wE-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.79A 1i3wF-2c34A:
undetectable		 1i3wF-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  32
PRO A  30
THR A  31
 None
 0.86A 1i3wG-2c34A:
undetectable		 1i3wG-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.85A 1i3wG-2c34A:
undetectable		 1i3wG-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.87A 1i3wH-2c34A:
undetectable		 1i3wH-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  32
PRO A  30
THR A  31
 None
 0.82A 1mnvD-2c34A:
undetectable		 1mnvD-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.75A 1mnvD-2c34A:
undetectable		 1mnvD-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  32
PRO A  30
THR A  31
 None
 0.85A 1ovfB-2c34A:
undetectable		 1ovfB-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.78A 1qfiA-2c34A:
undetectable		 1qfiA-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.82A 1unjF-2c34A:
undetectable		 1unjF-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.85A 1unjR-2c34A:
undetectable		 1unjR-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  31
THR A  32
PRO A  30
 None
 0.86A 1unmF-2c34A:
undetectable		 1unmF-2c34A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 2c34 INHIBITOR OF
CYSTEINE PEPTIDASES
(Leishmania
mexicana) 		3 / 3 THR A  32
PRO A  30
THR A  31
 None
 0.88A 4hivD-2c34A:
undetectable		 4hivD-2c34A:
8.25