SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YSI_A_NCAA1001_0 (UBIQUITINATING/DEUBI QUITINATING ENZYME SDEA)	2c3g	ALPHA-AMYLASE G-6 (Bacillus halodurans)	4 / 6	GLY A 56 SER A 59 THR A 27 VAL A 31	None	1.24A	5ysiA-2c3gA: undetectable	5ysiA-2c3gA: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_A_HISA402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	2c3g	ALPHA-AMYLASE G-6 (Bacillus halodurans)	5 / 10	GLY A 6 THR A 27 VAL A 60 VAL A 31 LEU A 22	None	1.11A	6czmA-2c3gA: undetectable 6czmC-2c3gA: undetectable	6czmA-2c3gA: 14.46 6czmC-2c3gA: 14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_B_HISB402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	2c3g	ALPHA-AMYLASE G-6 (Bacillus halodurans)	5 / 9	VAL A 31 LEU A 22 GLY A 6 THR A 27 VAL A 60	None	1.15A	6czmA-2c3gA: undetectable 6czmB-2c3gA: undetectable	6czmA-2c3gA: 14.46 6czmB-2c3gA: 14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_C_HISC402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	2c3g	ALPHA-AMYLASE G-6 (Bacillus halodurans)	5 / 9	VAL A 31 LEU A 22 GLY A 6 THR A 27 VAL A 60	None	1.18A	6czmB-2c3gA: undetectable 6czmC-2c3gA: undetectable	6czmB-2c3gA: 14.46 6czmC-2c3gA: 14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_E_HISE402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	2c3g	ALPHA-AMYLASE G-6 (Bacillus halodurans)	5 / 9	VAL A 31 LEU A 22 GLY A 6 THR A 27 VAL A 60	None	1.17A	6czmD-2c3gA: undetectable 6czmE-2c3gA: undetectable	6czmD-2c3gA: 14.46 6czmE-2c3gA: 14.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5YSI_A_NCAA1001_0","UBIQUITINATING\/DEUBIQUITINATING ENZYME SDEA","2c3g","ALPHA-AMYLASE G-6","Bacillus halodurans",4,"GLY A  56;SER A  59;THR A  27;VAL A  31","None","1.24A","5ysiA-2c3gA:undetectable","5ysiA-2c3gA:17.20"],["6CZM_A_HISA402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","2c3g","ALPHA-AMYLASE G-6","Bacillus halodurans",5,"GLY A   6;THR A  27;VAL A  60;VAL A  31;LEU A  22","None","1.11A","6czmA-2c3gA:undetectable;6czmC-2c3gA:undetectable","6czmA-2c3gA:14.46;6czmC-2c3gA:14.46"],["6CZM_B_HISB402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","2c3g","ALPHA-AMYLASE G-6","Bacillus halodurans",5,"VAL A  31;LEU A  22;GLY A   6;THR A  27;VAL A  60","None","1.15A","6czmA-2c3gA:undetectable;6czmB-2c3gA:undetectable","6czmA-2c3gA:14.46;6czmB-2c3gA:14.46"],["6CZM_C_HISC402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","2c3g","ALPHA-AMYLASE G-6","Bacillus halodurans",5,"VAL A  31;LEU A  22;GLY A   6;THR A  27;VAL A  60","None","1.18A","6czmB-2c3gA:undetectable;6czmC-2c3gA:undetectable","6czmB-2c3gA:14.46;6czmC-2c3gA:14.46"],["6CZM_E_HISE402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","2c3g","ALPHA-AMYLASE G-6","Bacillus halodurans",5,"VAL A  31;LEU A  22;GLY A   6;THR A  27;VAL A  60","None","1.17A","6czmD-2c3gA:undetectable;6czmE-2c3gA:undetectable","6czmD-2c3gA:14.46;6czmE-2c3gA:14.46"]]