SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c4m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.75A 1c8lA-2c4mA:
50.2		 1c8lA-2c4mA:
43.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 GLN A 347
ASP A 345
VAL A 392
GLY A 390
 None
 1.26A 1ekjC-2c4mA:
undetectable
1ekjD-2c4mA:
undetectable		 1ekjC-2c4mA:
15.25
1ekjD-2c4mA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 ASP A 345
VAL A 392
GLY A 390
GLN A 347
 None
 1.27A 1ekjC-2c4mA:
undetectable
1ekjD-2c4mA:
undetectable		 1ekjC-2c4mA:
15.25
1ekjD-2c4mA:
15.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.79A 1gfzA-2c4mA:
50.2		 1gfzA-2c4mA:
43.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.85A 1jnoA-2c4mA:
undetectable		 1jnoA-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.85A 1jnoB-2c4mA:
undetectable		 1jnoB-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 PHE A 263
LEU A 177
ALA A 267
TYR A 191
ILE A 189
 None
 1.20A 1kglA-2c4mA:
undetectable		 1kglA-2c4mA:
10.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.88A 1l5qA-2c4mA:
50.3		 1l5qA-2c4mA:
43.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.88A 1l5qB-2c4mA:
47.5		 1l5qB-2c4mA:
43.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.93A 1l7xA-2c4mA:
47.6		 1l7xA-2c4mA:
43.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.92A 1l7xB-2c4mA:
48.7		 1l7xB-2c4mA:
43.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.90A 1magA-2c4mA:
undetectable		 1magA-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.90A 1magB-2c4mA:
undetectable		 1magB-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 11 ALA A 188
GLU A 305
ARG A 308
LEU A 309
GLU A 313
 None
None
FMT  A1797 ( 4.4A)
None
None
 1.29A 1mjlA-2c4mA:
undetectable
1mjlB-2c4mA:
undetectable		 1mjlA-2c4mA:
9.53
1mjlB-2c4mA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 8 ILE A 558
GLY A 560
ILE A 610
SER A 614
 None
 0.87A 1mrjA-2c4mA:
undetectable		 1mrjA-2c4mA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MSK_A_SAMA1301_0
(COBALAMIN-DEPENDENT
METHIONINE SYNTHASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 ASP A 728
ARG A 569
ALA A 572
ALA A 563
TYR A 567
 None
 1.42A 1mskA-2c4mA:
0.0		 1mskA-2c4mA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.88A 1ng8A-2c4mA:
undetectable		 1ng8A-2c4mA:
2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.88A 1ng8B-2c4mA:
undetectable		 1ng8B-2c4mA:
2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.88A 1nrmA-2c4mA:
undetectable		 1nrmA-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.88A 1nrmB-2c4mA:
undetectable		 1nrmB-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.86A 1nruA-2c4mA:
undetectable		 1nruA-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.86A 1nruB-2c4mA:
undetectable		 1nruB-2c4mA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.86A 1nt6A-2c4mA:
undetectable		 1nt6A-2c4mA:
1.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ALA A 402
VAL A 325
TRP A 322
 None
 0.86A 1nt6B-2c4mA:
undetectable		 1nt6B-2c4mA:
1.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ILE A 577
ALA A 561
PHE A 559
SER A 621
ILE A 620
 None
 1.11A 1rx3A-2c4mA:
undetectable		 1rx3A-2c4mA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 4 ASP A 705
LEU A 714
LEU A 698
LEU A 710
 None
 1.42A 1u18A-2c4mA:
undetectable		 1u18A-2c4mA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ASP A 539
PHE A 736
ARG A 740
 None
 0.57A 2a3aA-2c4mA:
3.8		 2a3aA-2c4mA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 ILE A 405
ALA A 402
ALA A 330
ASN A 295
ALA A 401
 None
 1.09A 2aclC-2c4mA:
undetectable		 2aclC-2c4mA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 11 ILE A 405
ALA A 402
ALA A 330
ASN A 295
LEU A 294
ALA A 401
 None
 1.13A 2aclE-2c4mA:
undetectable		 2aclE-2c4mA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 SER A 268
ARG A 308
LEU A 309
GLU A 313
 None
FMT  A1797 ( 4.4A)
None
None
 1.03A 2cdqB-2c4mA:
3.4		 2cdqB-2c4mA:
22.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_A_ACRA992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		9 / 10 ASN A 112
LEU A 115
TYR A 245
ASP A 248
ARG A 257
ASP A 296
HIS A 298
HIS A 525
ALA A 564
 None
 0.70A 2ecpA-2c4mA:
50.5		 2ecpA-2c4mA:
45.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_B_ACRB992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		9 / 10 ASN A 112
LEU A 115
TYR A 245
ASP A 248
ARG A 257
ASP A 296
HIS A 298
HIS A 525
ALA A 564
 None
 0.68A 2ecpB-2c4mA:
49.1		 2ecpB-2c4mA:
45.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 LEU A 138
LEU A  69
MET A  70
 None
 0.79A 2itzA-2c4mA:
undetectable		 2itzA-2c4mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ARG A 446
ASP A 463
THR A 467
ASN A  76
 None
 1.23A 2jc9A-2c4mA:
2.5		 2jc9A-2c4mA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 LEU A  83
GLY A  82
MET A 447
PHE A 168
VAL A 466
 None
FMT  A1802 ( 4.2A)
None
None
None
 1.35A 2w8yA-2c4mA:
undetectable		 2w8yA-2c4mA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 VAL A 203
ILE A  44
GLY A 197
THR A 196
 None
 0.67A 2xrzB-2c4mA:
1.8		 2xrzB-2c4mA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 LEU A 445
TRP A 465
THR A 457
ASP A 463
TYR A 198
 None
None
None
None
FMT  A1802 (-3.1A)
 1.34A 2y00B-2c4mA:
undetectable		 2y00B-2c4mA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 LEU A 445
TRP A 465
THR A 457
ASP A 463
TYR A 198
 None
None
None
None
FMT  A1802 (-3.1A)
 1.33A 2y01B-2c4mA:
undetectable		 2y01B-2c4mA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 8 LEU A 244
GLY A 113
LEU A  69
GLY A  71
ASP A 107
 None
PO4  A1794 (-3.5A)
None
None
None
 1.40A 2yfxA-2c4mA:
undetectable		 2yfxA-2c4mA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.96A 3ag3A-2c4mA:
undetectable
3ag3J-2c4mA:
undetectable		 3ag3A-2c4mA:
19.75
3ag3J-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 LEU A 691
VAL A 537
ARG A 740
 None
 0.90A 3b0wB-2c4mA:
undetectable		 3b0wB-2c4mA:
14.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.80A 3dd1A-2c4mA:
49.9		 3dd1A-2c4mA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.84A 3dd1B-2c4mA:
47.0		 3dd1B-2c4mA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.83A 3ddsA-2c4mA:
48.0		 3ddsA-2c4mA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.82A 3ddsB-2c4mA:
46.8		 3ddsB-2c4mA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.85A 3ddwA-2c4mA:
48.0		 3ddwA-2c4mA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.86A 3ddwB-2c4mA:
47.2		 3ddwB-2c4mA:
42.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 4 LEU A  83
ALA A  39
VAL A  12
PRO A   8
 None
 1.14A 3gv1B-2c4mA:
undetectable		 3gv1B-2c4mA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 11 ASP A 705
LEU A 538
ILE A 580
ASP A 713
SER A 717
 None
 1.46A 3ko0E-2c4mA:
0.0
3ko0F-2c4mA:
undetectable
3ko0G-2c4mA:
0.0
3ko0H-2c4mA:
undetectable		 3ko0E-2c4mA:
7.79
3ko0F-2c4mA:
7.79
3ko0G-2c4mA:
7.79
3ko0H-2c4mA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 ASP A 713
SER A 717
ILE A 580
LEU A 703
ASP A 705
 None
 1.43A 3m0wC-2c4mA:
undetectable
3m0wD-2c4mA:
undetectable
3m0wE-2c4mA:
0.4
3m0wF-2c4mA:
undetectable		 3m0wC-2c4mA:
9.02
3m0wD-2c4mA:
9.02
3m0wE-2c4mA:
9.02
3m0wF-2c4mA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 9 LEU A 703
ASP A 705
ILE A 580
ASP A 713
SER A 717
 None
 1.46A 3m0wC-2c4mA:
undetectable
3m0wD-2c4mA:
undetectable
3m0wE-2c4mA:
0.4
3m0wF-2c4mA:
undetectable		 3m0wC-2c4mA:
9.02
3m0wD-2c4mA:
9.02
3m0wE-2c4mA:
9.02
3m0wF-2c4mA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 LEU A 535
VAL A 688
TYR A 685
GLY A 690
LEU A 733
 None
 1.29A 3medA-2c4mA:
undetectable
3medB-2c4mA:
undetectable		 3medA-2c4mA:
21.18
3medB-2c4mA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ASN A 285
ALA A 287
THR A 328
LEU A 306
 None
 0.93A 3t3sC-2c4mA:
undetectable		 3t3sC-2c4mA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 4 ASP A 464
ASP A 463
GLY A 199
THR A  79
 None
None
FMT  A1802 (-3.1A)
None
 1.36A 3tl9B-2c4mA:
undetectable		 3tl9B-2c4mA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 9 ILE A 577
ALA A 561
PHE A 559
SER A 621
ILE A 620
 None
 1.00A 3tq8A-2c4mA:
undetectable		 3tq8A-2c4mA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 5 LEU A 540
ARG A 555
PRO A 553
ALA A 554
 None
 1.37A 3vm4A-2c4mA:
undetectable		 3vm4A-2c4mA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ALA A 267
PHE A 263
ILE A 170
ASP A 192
ARG A 207
 None
None
None
None
FMT  A1795 ( 3.8A)
 1.46A 3welA-2c4mA:
undetectable		 3welA-2c4mA:
22.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 6 MET A 311
GLY A 317
TRP A 318
ARG A 355
GLU A 362
ARG A 366
 FMT  A1803 ( 4.3A)
None
None
FMT  A1803 (-2.9A)
None
None
 0.45A 4bqfA-2c4mA:
53.0		 4bqfA-2c4mA:
42.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 8 MET A 311
TRP A 318
ARG A 355
GLU A 358
GLU A 362
ARG A 366
 FMT  A1803 ( 4.3A)
None
FMT  A1803 (-2.9A)
None
None
None
 0.42A 4bqfB-2c4mA:
53.8		 4bqfB-2c4mA:
42.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 5 LEU A 310
LEU A 306
MET A 272
THR A 328
 None
None
FMT  A1795 (-4.9A)
None
 1.13A 4do3A-2c4mA:
undetectable		 4do3A-2c4mA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 TYR A 536
VAL A 537
LEU A 540
VAL A 590
 None
 1.12A 4e1gB-2c4mA:
undetectable		 4e1gB-2c4mA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 8 ASN A 285
ALA A 287
THR A 328
LEU A 306
 None
 0.91A 4ejgB-2c4mA:
undetectable		 4ejgB-2c4mA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 6 ASN A 285
ALA A 287
THR A 328
LEU A 306
 None
 0.88A 4ejgD-2c4mA:
undetectable		 4ejgD-2c4mA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 11 GLY A 114
ARG A 117
ALA A 120
GLY A 111
ALA A 271
 PO4  A1794 (-3.4A)
None
None
None
FMT  A1795 ( 3.8A)
 1.18A 4l6v1-2c4mA:
undetectable
4l6v6-2c4mA:
undetectable		 4l6v1-2c4mA:
21.00
4l6v6-2c4mA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 5 PRO A 194
GLY A 204
ASP A 107
ASP A 124
 None
FMT  A1798 (-3.7A)
None
None
 1.08A 4n48B-2c4mA:
undetectable		 4n48B-2c4mA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 9 ASN A 764
ILE A 664
GLY A 644
MET A 646
VAL A 657
 None
 1.09A 4nptA-2c4mA:
undetectable		 4nptA-2c4mA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 8 LEU A 540
VAL A 557
VAL A 584
TYR A 536
 None
 1.01A 4puoC-2c4mA:
undetectable		 4puoC-2c4mA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ASN A  77
ARG A 443
GLY A  71
ALA A 108
PHE A 168
 None
 1.48A 4ryaA-2c4mA:
undetectable		 4ryaA-2c4mA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 THR A  51
GLY A 204
ASP A 774
ALA A 781
THR A 782
 FMT  A1798 ( 4.6A)
FMT  A1798 (-3.7A)
None
None
None
 1.12A 4uckB-2c4mA:
undetectable		 4uckB-2c4mA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 9 LEU A 576
ALA A 534
LEU A 531
LEU A 718
LEU A 695
ALA A 694
 None
 1.24A 4z91F-2c4mA:
1.3
4z91G-2c4mA:
1.3
4z91H-2c4mA:
2.0
4z91I-2c4mA:
1.3
4z91J-2c4mA:
1.3		 4z91F-2c4mA:
18.24
4z91G-2c4mA:
18.24
4z91H-2c4mA:
18.24
4z91I-2c4mA:
18.24
4z91J-2c4mA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 9 LEU A 695
ALA A 694
LEU A 576
ALA A 534
LEU A 531
LEU A 718
 None
 1.26A 4z91F-2c4mA:
1.3
4z91G-2c4mA:
1.3
4z91H-2c4mA:
2.0
4z91I-2c4mA:
1.3
4z91J-2c4mA:
1.3		 4z91F-2c4mA:
18.24
4z91G-2c4mA:
18.24
4z91H-2c4mA:
18.24
4z91I-2c4mA:
18.24
4z91J-2c4mA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 9 LEU A 698
LEU A 576
ALA A 534
LEU A 531
LEU A 718
LEU A 695
 None
 1.26A 4z91F-2c4mA:
1.3
4z91G-2c4mA:
1.3
4z91H-2c4mA:
2.0
4z91I-2c4mA:
1.3
4z91J-2c4mA:
1.3		 4z91F-2c4mA:
18.24
4z91G-2c4mA:
18.24
4z91H-2c4mA:
18.24
4z91I-2c4mA:
18.24
4z91J-2c4mA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.89A 5b1aA-2c4mA:
2.5
5b1aJ-2c4mA:
undetectable		 5b1aA-2c4mA:
19.75
5b1aJ-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.90A 5b3sA-2c4mA:
2.8
5b3sJ-2c4mA:
undetectable		 5b3sA-2c4mA:
19.75
5b3sJ-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ALA A 119
GLY A 111
GLY A 116
GLY A 114
LEU A 110
 None
None
None
PO4  A1794 (-3.4A)
None
 0.90A 5c0oH-2c4mA:
3.1		 5c0oH-2c4mA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 PHE A 286
ILE A 273
ASP A 315
 None
 0.66A 5cswA-2c4mA:
0.9		 5cswA-2c4mA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 PHE A 286
ILE A 273
ASP A 315
 None
 0.55A 5cswB-2c4mA:
undetectable		 5cswB-2c4mA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 8 ALA A 287
HIS A 280
ASN A 285
HIS A  62
 None
 1.31A 5db5A-2c4mA:
undetectable
5db5B-2c4mA:
undetectable		 5db5A-2c4mA:
20.62
5db5B-2c4mA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 ALA A  90
GLU A  93
LEU A  94
GLY A  35
LEU A  36
 None
 1.37A 5dx3A-2c4mA:
undetectable		 5dx3A-2c4mA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 ALA A  90
GLU A  93
LEU A  94
GLY A  35
LEU A  36
 None
 1.38A 5dxbA-2c4mA:
undetectable		 5dxbA-2c4mA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 PHE A 263
LEU A 177
ALA A 267
TYR A 191
ILE A 189
 None
 1.15A 5h8tA-2c4mA:
undetectable		 5h8tA-2c4mA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ILE A 664
GLY A 644
ALA A 662
PHE A 771
VAL A 657
 None
 1.12A 5hw4A-2c4mA:
1.8		 5hw4A-2c4mA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 11 ILE A 664
GLY A 644
ALA A 662
PHE A 771
VAL A 657
 None
 1.08A 5hw4B-2c4mA:
undetectable		 5hw4B-2c4mA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ILE A 664
GLY A 644
ALA A 662
PHE A 771
VAL A 657
 None
 1.06A 5hw4C-2c4mA:
1.8		 5hw4C-2c4mA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 8 TYR A  63
PHE A 122
ILE A 784
TRP A 785
 None
 0.89A 5hw8H-2c4mA:
undetectable		 5hw8H-2c4mA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 VAL A 651
GLU A 671
GLU A 670
 None
 0.68A 5jsdB-2c4mA:
undetectable
5jsdC-2c4mA:
undetectable		 5jsdB-2c4mA:
22.01
5jsdC-2c4mA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 PHE A 263
LEU A 177
ALA A 267
TYR A 191
ILE A 189
 None
 1.22A 5ljbA-2c4mA:
undetectable		 5ljbA-2c4mA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 PHE A 263
LEU A 177
ALA A 267
TYR A 191
ILE A 189
 None
 1.24A 5ljcA-2c4mA:
undetectable		 5ljcA-2c4mA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 VAL A 292
SER A 284
LEU A 283
HIS A 280
LEU A 277
 None
 1.21A 5ubbA-2c4mA:
undetectable		 5ubbA-2c4mA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ARG A 368
ARG A 371
ARG A 366
 None
 0.86A 5vcgA-2c4mA:
undetectable		 5vcgA-2c4mA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 10 GLY A 114
HIS A 334
VAL A 408
ASN A 437
LYS A 528
GLU A 626
 PO4  A1794 (-3.4A)
FMT  A1799 (-3.9A)
None
FMT  A1799 (-3.5A)
PO4  A1794 ( 3.9A)
None
 0.91A 5vncC-2c4mA:
17.1		 5vncC-2c4mA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 10 GLY A 114
HIS A 334
VAL A 408
ASN A 437
LYS A 528
GLY A 629
 PO4  A1794 (-3.4A)
FMT  A1799 (-3.9A)
None
FMT  A1799 (-3.5A)
PO4  A1794 ( 3.9A)
PLP  A1634 ( 3.8A)
 0.78A 5vncC-2c4mA:
17.1		 5vncC-2c4mA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 9 ALA A  90
GLU A  93
LEU A  94
GLY A  35
LEU A  36
 None
 1.30A 5wgqA-2c4mA:
undetectable		 5wgqA-2c4mA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.88A 5xdqN-2c4mA:
2.5
5xdqW-2c4mA:
undetectable		 5xdqN-2c4mA:
19.75
5xdqW-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.87A 5xdxA-2c4mA:
2.4
5xdxJ-2c4mA:
undetectable		 5xdxA-2c4mA:
19.75
5xdxJ-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.89A 5zcpA-2c4mA:
2.6
5zcpJ-2c4mA:
undetectable		 5zcpA-2c4mA:
19.75
5zcpJ-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 7 ILE A 491
LEU A 488
THR A 457
LEU A 456
 None
 0.89A 5zcqA-2c4mA:
2.2
5zcqJ-2c4mA:
undetectable		 5zcqA-2c4mA:
19.75
5zcqJ-2c4mA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 ILE A 544
ILE A 577
ALA A 534
LEU A 538
ALA A 694
 None
 1.31A 5zjiB-2c4mA:
undetectable		 5zjiB-2c4mA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 11 ASP A 728
ARG A 569
ALA A 572
ALA A 563
TYR A 567
 None
 1.45A 6bm5A-2c4mA:
0.0		 6bm5A-2c4mA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 LEU A 535
VAL A 688
TYR A 685
GLY A 690
LEU A 733
 None
 1.36A 6bsgA-2c4mA:
undetectable		 6bsgA-2c4mA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 LEU A 535
VAL A 688
TYR A 685
GLY A 690
LEU A 733
 None
 1.35A 6bsiA-2c4mA:
2.6		 6bsiA-2c4mA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 MET A 307
PHE A 349
VAL A 258
VAL A 392
ALA A 401
 None
 1.19A 6djzA-2c4mA:
undetectable		 6djzA-2c4mA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 GLY A 113
GLY A 114
ASP A 296
VAL A 408
ASN A 437
 PO4  A1794 (-3.5A)
PO4  A1794 (-3.4A)
None
None
FMT  A1799 (-3.5A)
 0.85A 6gneA-2c4mA:
23.3		 6gneA-2c4mA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 GLY A 113
GLY A 114
VAL A 408
ASN A 437
GLY A 629
 PO4  A1794 (-3.5A)
PO4  A1794 (-3.4A)
None
FMT  A1799 (-3.5A)
PLP  A1634 ( 3.8A)
 0.83A 6gneA-2c4mA:
23.3		 6gneA-2c4mA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 12 GLU A  67
GLY A 113
GLY A 114
ASP A 296
VAL A 408
ASN A 437
 None
PO4  A1794 (-3.5A)
PO4  A1794 (-3.4A)
None
None
FMT  A1799 (-3.5A)
 0.81A 6gneB-2c4mA:
23.1		 6gneB-2c4mA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 12 GLU A  67
GLY A 113
GLY A 114
VAL A 408
ASN A 437
GLY A 629
 None
PO4  A1794 (-3.5A)
PO4  A1794 (-3.4A)
None
FMT  A1799 (-3.5A)
PLP  A1634 ( 3.8A)
 0.78A 6gneB-2c4mA:
23.1		 6gneB-2c4mA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ASP A 248
ASP A 296
HIS A 298
ASN A 437
GLU A 626
 None
None
None
FMT  A1799 (-3.5A)
None
 1.01A 6gnfA-2c4mA:
23.0		 6gnfA-2c4mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 9 GLY A 113
GLY A 114
TYR A 245
HIS A 334
VAL A 408
 PO4  A1794 (-3.5A)
PO4  A1794 (-3.4A)
None
FMT  A1799 (-3.9A)
None
 0.92A 6gnfA-2c4mA:
23.0		 6gnfA-2c4mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 10 GLY A 114
LEU A 115
TYR A 245
HIS A 334
VAL A 408
 PO4  A1794 (-3.4A)
None
None
FMT  A1799 (-3.9A)
None
 0.90A 6gnfC-2c4mA:
22.7		 6gnfC-2c4mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 ASP A 248
ASP A 296
HIS A 298
ASN A 437
GLU A 626
 None
None
None
FMT  A1799 (-3.5A)
None
 1.02A 6gnfC-2c4mA:
22.8		 6gnfC-2c4mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 GLY A 113
LEU A 115
ASP A 248
ASP A 296
ASN A 437
 PO4  A1794 (-3.5A)
None
None
None
FMT  A1799 (-3.5A)
 1.01A 6gngA-2c4mA:
22.4		 6gngA-2c4mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 GLY A 113
LEU A 115
ASP A 296
HIS A 298
ASN A 437
 PO4  A1794 (-3.5A)
None
None
None
FMT  A1799 (-3.5A)
 0.80A 6gngA-2c4mA:
22.4		 6gngA-2c4mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 GLU A  67
GLY A 114
TYR A 245
HIS A 334
GLU A 626
 None
PO4  A1794 (-3.4A)
None
FMT  A1799 (-3.9A)
None
 0.82A 6gngA-2c4mA:
22.4		 6gngA-2c4mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		6 / 12 GLU A  67
GLY A 114
TYR A 245
HIS A 334
VAL A 408
GLY A 629
 None
PO4  A1794 (-3.4A)
None
FMT  A1799 (-3.9A)
None
PLP  A1634 ( 3.8A)
 0.87A 6gngA-2c4mA:
22.4		 6gngA-2c4mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		5 / 12 GLU A  67
GLY A 113
GLY A 114
LEU A 115
HIS A 298
 None
PO4  A1794 (-3.5A)
PO4  A1794 (-3.4A)
None
None
 0.38A 6gngB-2c4mA:
22.2		 6gngB-2c4mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		3 / 3 ASP A 248
ASP A 296
ASN A 437
 None
None
FMT  A1799 (-3.5A)
 0.81A 6gngB-2c4mA:
22.4		 6gngB-2c4mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 2c4m GLYCOGEN
PHOSPHORYLASE
(Corynebacterium
callunae) 		4 / 5 GLY A 116
LEU A 115
SER A  65
TYR A  63
 None
 1.01A 6ji6A-2c4mA:
undetectable		 6ji6A-2c4mA:
14.85