SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c6w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_A_CFXA1300_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	8 / 12	SER B 370 LYS B 373 SER B 428 ASN B 430 ASN B 562 THR B 543 LYS B 557 GLY B 559	CL B 704 (-3.5A) None CL B 704 (-3.4A) None None CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	1.05A	1i2wA-2c6wB: 16.4	1i2wA-2c6wB: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_B_CFXB2300_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	7 / 12	SER B 370 LYS B 373 SER B 428 ASN B 430 ASN B 562 THR B 543 GLY B 559	CL B 704 (-3.5A) None CL B 704 (-3.4A) None None CL B 704 ( 4.8A) CL B 704 ( 4.0A)	1.09A	1i2wB-2c6wB: 16.6	1i2wB-2c6wB: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N2X_B_SAMB402_1 (S-ADENOSYL-METHYLTRA NSFERASE MRAW)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	ASP B 335 VAL B 336 SER B 592 ASP B 303	None	1.38A	1n2xB-2c6wB: undetectable	1n2xB-2c6wB: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_B_BEZB504_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 7	LEU B 421 ALA B 424 ILE B 465 PRO B 432	None	0.95A	1oniB-2c6wB: undetectable 1oniC-2c6wB: undetectable	1oniB-2c6wB: 17.36 1oniC-2c6wB: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.92A	1v54A-2c6wB: undetectable 1v54J-2c6wB: undetectable	1v54A-2c6wB: 21.23 1v54J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOS_A_VIAA1_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	MET B 372 ASP B 377 PHE B 490 SER B 592 ILE B 454	None	1.32A	1xosA-2c6wB: undetectable	1xosA-2c6wB: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YMX_A_CFXA1001_1 (BETA-LACTAMASE CTX-M-9)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	LYS B 373 SER B 428 ASN B 430 THR B 543 LYS B 557 GLY B 559	None CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.77A	1ymxA-2c6wB: 16.9	1ymxA-2c6wB: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YMX_A_CFXA1001_1 (BETA-LACTAMASE CTX-M-9)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 ASN B 430 THR B 543 LYS B 557 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.57A	1ymxA-2c6wB: 16.9	1ymxA-2c6wB: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1H_A_GBNA502_1 (BRANCHED CHAIN AMINOTRANSFERASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 8	GLY B 586 ALA B 594 TYR B 314 VAL B 329	None	0.83A	2a1hA-2c6wB: undetectable 2a1hB-2c6wB: undetectable	2a1hA-2c6wB: 19.08 2a1hB-2c6wB: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1H_B_GBNB501_1 (BRANCHED CHAIN AMINOTRANSFERASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 8	TYR B 314 VAL B 329 GLY B 586 ALA B 594	None	0.81A	2a1hA-2c6wB: undetectable 2a1hB-2c6wB: undetectable	2a1hA-2c6wB: 19.08 2a1hB-2c6wB: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.95A	2dyrA-2c6wB: undetectable 2dyrJ-2c6wB: undetectable	2dyrA-2c6wB: 21.23 2dyrJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_J_CHDJ101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.94A	2dysA-2c6wB: undetectable 2dysJ-2c6wB: undetectable	2dysA-2c6wB: 21.23 2dysJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_W_CHDW101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.88A	2dysN-2c6wB: 0.0 2dysW-2c6wB: undetectable	2dysN-2c6wB: 21.23 2dysW-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 8	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.87A	2einA-2c6wB: undetectable 2einJ-2c6wB: undetectable	2einA-2c6wB: 21.23 2einJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JST_A_HLTA101_1 (FOUR-ALPHA-HELIX BUNDLE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TRP B 596 ALA B 361 LEU B 583 ALA B 330	None	1.30A	2jstA-2c6wB: undetectable 2jstB-2c6wB: undetectable	2jstA-2c6wB: 8.71 2jstB-2c6wB: 8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YZQ_A_SAMA6075_0 (PUTATIVE UNCHARACTERIZED PROTEIN PH1780)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	THR B 300 VAL B 302 ILE B 342 GLU B 481 GLN B 344	None	1.22A	2yzqA-2c6wB: undetectable	2yzqA-2c6wB: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.02A	2zxwA-2c6wB: 0.0 2zxwJ-2c6wB: undetectable	2zxwA-2c6wB: 21.23 2zxwJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.00A	3abkN-2c6wB: undetectable 3abkW-2c6wB: undetectable	3abkN-2c6wB: 21.23 3abkW-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.01A	3abmA-2c6wB: undetectable 3abmJ-2c6wB: undetectable	3abmA-2c6wB: 21.23 3abmJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.03A	3ag1J-2c6wB: undetectable	3ag1J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.91A	3ag2J-2c6wB: undetectable	3ag2J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 7	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.87A	3ag2N-2c6wB: undetectable 3ag2W-2c6wB: undetectable	3ag2N-2c6wB: 21.23 3ag2W-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.06A	3ag4J-2c6wB: undetectable	3ag4J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.96A	3asnA-2c6wB: undetectable 3asnJ-2c6wB: undetectable	3asnA-2c6wB: 21.23 3asnJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.95A	3asoA-2c6wB: undetectable 3asoJ-2c6wB: undetectable	3asoA-2c6wB: 21.23 3asoJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_A_V2HA602_1 (CYTOCHROME P450 2R1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 5	ASN B 365 ALA B 347 LEU B 327 GLY B 598 THR B 371	None	1.26A	3dl9A-2c6wB: undetectable	3dl9A-2c6wB: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HLW_A_CE3A301_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	LYS B 373 SER B 428 ASN B 430 THR B 543 LYS B 557 GLY B 559	None CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.67A	3hlwA-2c6wB: 16.8	3hlwA-2c6wB: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HLW_B_CE3B302_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 428 ASN B 430 THR B 543 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.50A	3hlwB-2c6wB: 17.0	3hlwB-2c6wB: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA308_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.73A	3ny4A-2c6wB: 16.5	3ny4A-2c6wB: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA308_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.71A	3ny4A-2c6wB: 16.5	3ny4A-2c6wB: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q07_A_WPPA300_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	LYS B 373 SER B 428 ASN B 430 LYS B 557 GLY B 559	None CL B 704 (-3.4A) None None CL B 704 ( 4.0A)	0.63A	3q07A-2c6wB: 16.8	3q07A-2c6wB: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SH8_A_CEDA1_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 ASN B 430 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) None None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.67A	3sh8A-2c6wB: 16.6	3sh8A-2c6wB: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 6	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.99A	3wg7A-2c6wB: undetectable 3wg7J-2c6wB: undetectable	3wg7A-2c6wB: 21.23 3wg7J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E0F_A_RBFA301_1 (RIBOFLAVIN SYNTHASE SUBUNIT ALPHA)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 11	SER B 389 VAL B 394 LEU B 421 THR B 390 ALA B 424	None	1.23A	4e0fA-2c6wB: undetectable	4e0fA-2c6wB: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EUZ_A_MEMA401_1 (CARBAPENEM-HYDROLIZI NG BETA-LACTAMASE SFC-1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	8 / 12	LYS B 373 SER B 428 ASN B 430 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	None CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.93A	4euzA-2c6wB: 16.3	4euzA-2c6wB: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FH2_A_0RNA303_1 (BETA-LACTAMASE SHV-1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 10	SER B 428 ASN B 430 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.4A) None None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.65A	4fh2A-2c6wB: 16.0	4fh2A-2c6wB: 19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N9K_A_CEDA301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 ASN B 430 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) None None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.65A	4n9kA-2c6wB: 16.6	4n9kA-2c6wB: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N9K_B_CEDB301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 ASN B 430 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) None None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.63A	4n9kB-2c6wB: 16.6	4n9kB-2c6wB: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJK_A_SAMA302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	THR B 332 GLU B 481 ASN B 274 VAL B 279 GLN B 282	None	1.34A	4njkA-2c6wB: undetectable	4njkA-2c6wB: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM5_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 428 ASN B 430 THR B 543 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.69A	4pm5A-2c6wB: 17.0	4pm5A-2c6wB: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM7_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	LYS B 373 SER B 428 ASN B 430 THR B 543 LYS B 557 GLY B 559	None CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.84A	4pm7A-2c6wB: 17.1	4pm7A-2c6wB: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM9_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 428 ASN B 430 THR B 543 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.71A	4pm9A-2c6wB: 17.1	4pm9A-2c6wB: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 9	ALA B 489 THR B 495 ALA B 522 GLY B 339 ALA B 485	None	1.16A	4qvnK-2c6wB: undetectable 4qvnL-2c6wB: undetectable	4qvnK-2c6wB: 19.90 4qvnL-2c6wB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 9	ALA B 489 THR B 495 ALA B 522 GLY B 339 ALA B 485	None	1.16A	4qvnY-2c6wB: undetectable 4qvnZ-2c6wB: undetectable	4qvnY-2c6wB: 19.90 4qvnZ-2c6wB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 9	ALA B 489 THR B 495 ALA B 522 GLY B 339 ALA B 485	None	1.16A	4qvqK-2c6wB: undetectable 4qvqL-2c6wB: undetectable	4qvqK-2c6wB: 18.86 4qvqL-2c6wB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 9	ALA B 489 THR B 495 ALA B 522 GLY B 339 ALA B 485	None	1.16A	4qvqY-2c6wB: undetectable 4qvqZ-2c6wB: undetectable	4qvqY-2c6wB: 18.86 4qvqZ-2c6wB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHZ_A_CEDA301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 11	SER B 370 SER B 428 ASN B 430 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) None None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.66A	5ghzA-2c6wB: 16.6	5ghzA-2c6wB: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHZ_B_CEDB301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 10	SER B 370 SER B 428 ASN B 430 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) None None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.65A	5ghzB-2c6wB: 16.6	5ghzB-2c6wB: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 7	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.91A	5iy5N-2c6wB: undetectable 5iy5W-2c6wB: undetectable	5iy5N-2c6wB: 21.23 5iy5W-2c6wB: 8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 9	ALA B 489 THR B 495 ALA B 522 GLY B 339 ALA B 485	None	1.03A	5l5zK-2c6wB: undetectable 5l5zL-2c6wB: undetectable	5l5zK-2c6wB: 20.49 5l5zL-2c6wB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 9	ALA B 489 THR B 495 ALA B 522 GLY B 339 ALA B 485	None	1.03A	5l5zY-2c6wB: undetectable 5l5zZ-2c6wB: undetectable	5l5zY-2c6wB: 20.49 5l5zZ-2c6wB: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LAK_I_BEZI1_0 (3CL PROTEASE BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	3 / 3	SER B 462 TYR B 461 TYR B 401	None	0.84A	5lakA-2c6wB: undetectable 5lakI-2c6wB: undetectable	5lakA-2c6wB: 22.95 5lakI-2c6wB: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LAK_J_BEZJ1_0 (3CL PROTEASE BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	3 / 3	SER B 462 TYR B 461 TYR B 401	None	0.85A	5lakC-2c6wB: undetectable 5lakJ-2c6wB: undetectable	5lakC-2c6wB: 22.95 5lakJ-2c6wB: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OJ0_A_9WTA801_0 (PENICILLIN-BINDING PROTEIN 2X)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	ARG B 413 SER B 428 ASN B 430 THR B 543 GLY B 559 THR B 560	None CL B 704 (-3.4A) None CL B 704 ( 4.8A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	1.14A	5oj0A-2c6wB: 26.5	5oj0A-2c6wB: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OJ0_A_9WTA801_0 (PENICILLIN-BINDING PROTEIN 2X)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	TRP B 411 SER B 428 ASN B 430 GLY B 559 THR B 560	None CL B 704 (-3.4A) None CL B 704 ( 4.0A) CL B 704 ( 4.8A)	1.24A	5oj0A-2c6wB: 26.5	5oj0A-2c6wB: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W97_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.80A	5w97J-2c6wB: undetectable	5w97J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.92A	5wauJ-2c6wB: undetectable	5wauJ-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.18A	5x1bW-2c6wB: undetectable	5x1bW-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	0.89A	5x1fW-2c6wB: undetectable	5x1fW-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	ARG B 619 MET B 621 THR B 623 LEU B 625	None	1.29A	5z86J-2c6wB: undetectable	5z86J-2c6wB: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZMQ_K_PACK1_0 (SERINE PROTEASE NS3 PEPTIDE PAC-DLY-DLY-DAR)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	3 / 3	ALA B 343 VAL B 279 TYR B 501	None	0.71A	5zmqH-2c6wB: undetectable	5zmqH-2c6wB: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_B_9F2B400_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.73A	6b5yB-2c6wB: 6.5	6b5yB-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_B_9F2B400_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.78A	6b5yB-2c6wB: 6.5	6b5yB-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_D_9F2D400_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	SER B 370 SER B 428 THR B 543 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.45A	6b5yD-2c6wB: 16.6	6b5yD-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_B_9F2B301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A)	0.59A	6b68B-2c6wB: 16.5	6b68B-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_B_9F2B301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.66A	6b68B-2c6wB: 16.5	6b68B-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_D_9F2D400_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.68A	6b68D-2c6wB: 16.5	6b68D-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_D_9F2D400_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	SER B 428 THR B 543 LYS B 557 GLY B 559 THR B 560	CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.69A	6b68D-2c6wB: 16.5	6b68D-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_B_9F2B301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	7 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.72A	6b69A-2c6wB: 16.5 6b69B-2c6wB: 16.5	6b69A-2c6wB: 12.46 6b69B-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_D_9F2D301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	7 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.72A	6b69D-2c6wB: 6.8	6b69D-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_B_9F2B301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	7 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.77A	6b6aB-2c6wB: 16.6	6b6aB-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_D_9F2D301_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	6 / 12	SER B 370 SER B 428 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.5A) CL B 704 (-3.4A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.80A	6b6aD-2c6wB: 16.6	6b6aD-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6D_A_9F2A302_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	7 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.86A	6b6dA-2c6wB: 16.5	6b6dA-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6E_A_9F2A302_1 (BETA-LACTAMASE)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	7 / 12	SER B 370 SER B 428 THR B 543 LYS B 557 THR B 558 GLY B 559 THR B 560	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 (-4.5A) CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.75A	6b6eA-2c6wB: 16.7	6b6eA-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C79_A_CE3A301_1 (BETA-LACTAMASE TOHO-1)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	SER B 428 ASN B 430 THR B 543 LYS B 557 GLY B 559	CL B 704 (-3.4A) None CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.49A	6c79A-2c6wB: 16.8	6c79A-2c6wB: 15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7L_B_Y00B405_0 (BETA-1 ADRENERGIC RECEPTOR)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	5 / 12	VAL B 298 SER B 480 SER B 479 ASN B 359 VAL B 279	None	1.42A	6h7lB-2c6wB: undetectable	6h7lB-2c6wB: 10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	4 / 5	TYR B 618 ARG B 619 MET B 622 THR B 623	None	1.14A	6nknJ-2c6wB: undetectable	6nknJ-2c6wB: 8.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1I2W_A_CFXA1300_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",8,"SER B 370;LYS B 373;SER B 428;ASN B 430;ASN B 562;THR B 543;LYS B 557;GLY B 559"," CL B 704 (-3.5A);None; CL B 704 (-3.4A);None;None; CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","1.05A","1i2wA-2c6wB:16.4","1i2wA-2c6wB:22.65"],["1I2W_B_CFXB2300_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",7,"SER B 370;LYS B 373;SER B 428;ASN B 430;ASN B 562;THR B 543;GLY B 559"," CL B 704 (-3.5A);None; CL B 704 (-3.4A);None;None; CL B 704 ( 4.8A); CL B 704 ( 4.0A)","1.09A","1i2wB-2c6wB:16.6","1i2wB-2c6wB:22.65"],["1N2X_B_SAMB402_1","S-ADENOSYL-METHYLTRANSFERASE MRAW","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"ASP B 335;VAL B 336;SER B 592;ASP B 303","None","1.38A","1n2xB-2c6wB:undetectable","1n2xB-2c6wB:21.36"],["1ONI_B_BEZB504_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"LEU B 421;ALA B 424;ILE B 465;PRO B 432","None","0.95A","1oniB-2c6wB:undetectable;1oniC-2c6wB:undetectable","1oniB-2c6wB:17.36;1oniC-2c6wB:17.36"],["1V54_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.92A","1v54A-2c6wB:undetectable;1v54J-2c6wB:undetectable","1v54A-2c6wB:21.23;1v54J-2c6wB:8.29"],["1XOS_A_VIAA1_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"MET B 372;ASP B 377;PHE B 490;SER B 592;ILE B 454","None","1.32A","1xosA-2c6wB:undetectable","1xosA-2c6wB:20.97"],["1YMX_A_CFXA1001_1","BETA-LACTAMASE CTX-M-9","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"LYS B 373;SER B 428;ASN B 430;THR B 543;LYS B 557;GLY B 559","None; CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.77A","1ymxA-2c6wB:16.9","1ymxA-2c6wB:23.08"],["1YMX_A_CFXA1001_1","BETA-LACTAMASE CTX-M-9","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;ASN B 430;THR B 543;LYS B 557;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.57A","1ymxA-2c6wB:16.9","1ymxA-2c6wB:23.08"],["2A1H_A_GBNA502_1","BRANCHED CHAIN AMINOTRANSFERASE;BRANCHED CHAIN AMINOTRANSFERASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"GLY B 586;ALA B 594;TYR B 314;VAL B 329","None","0.83A","2a1hA-2c6wB:undetectable;2a1hB-2c6wB:undetectable","2a1hA-2c6wB:19.08;2a1hB-2c6wB:19.08"],["2A1H_B_GBNB501_1","BRANCHED CHAIN AMINOTRANSFERASE;BRANCHED CHAIN AMINOTRANSFERASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 314;VAL B 329;GLY B 586;ALA B 594","None","0.81A","2a1hA-2c6wB:undetectable;2a1hB-2c6wB:undetectable","2a1hA-2c6wB:19.08;2a1hB-2c6wB:19.08"],["2DYR_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.95A","2dyrA-2c6wB:undetectable;2dyrJ-2c6wB:undetectable","2dyrA-2c6wB:21.23;2dyrJ-2c6wB:8.29"],["2DYS_J_CHDJ101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.94A","2dysA-2c6wB:undetectable;2dysJ-2c6wB:undetectable","2dysA-2c6wB:21.23;2dysJ-2c6wB:8.29"],["2DYS_W_CHDW101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.88A","2dysN-2c6wB:0.0;2dysW-2c6wB:undetectable","2dysN-2c6wB:21.23;2dysW-2c6wB:8.29"],["2EIN_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.87A","2einA-2c6wB:undetectable;2einJ-2c6wB:undetectable","2einA-2c6wB:21.23;2einJ-2c6wB:8.29"],["2JST_A_HLTA101_1","FOUR-ALPHA-HELIX BUNDLE;FOUR-ALPHA-HELIX BUNDLE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TRP B 596;ALA B 361;LEU B 583;ALA B 330","None","1.30A","2jstA-2c6wB:undetectable;2jstB-2c6wB:undetectable","2jstA-2c6wB:8.71;2jstB-2c6wB:8.71"],["2YZQ_A_SAMA6075_0","PUTATIVE UNCHARACTERIZED PROTEIN PH1780","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"THR B 300;VAL B 302;ILE B 342;GLU B 481;GLN B 344","None","1.22A","2yzqA-2c6wB:undetectable","2yzqA-2c6wB:22.14"],["2ZXW_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.02A","2zxwA-2c6wB:0.0;2zxwJ-2c6wB:undetectable","2zxwA-2c6wB:21.23;2zxwJ-2c6wB:8.29"],["3ABK_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.00A","3abkN-2c6wB:undetectable;3abkW-2c6wB:undetectable","3abkN-2c6wB:21.23;3abkW-2c6wB:8.29"],["3ABM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.01A","3abmA-2c6wB:undetectable;3abmJ-2c6wB:undetectable","3abmA-2c6wB:21.23;3abmJ-2c6wB:8.29"],["3AG1_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.03A","3ag1J-2c6wB:undetectable","3ag1J-2c6wB:8.29"],["3AG2_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.91A","3ag2J-2c6wB:undetectable","3ag2J-2c6wB:8.29"],["3AG2_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.87A","3ag2N-2c6wB:undetectable;3ag2W-2c6wB:undetectable","3ag2N-2c6wB:21.23;3ag2W-2c6wB:8.29"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.06A","3ag4J-2c6wB:undetectable","3ag4J-2c6wB:8.29"],["3ASN_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.96A","3asnA-2c6wB:undetectable;3asnJ-2c6wB:undetectable","3asnA-2c6wB:21.23;3asnJ-2c6wB:8.29"],["3ASO_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.95A","3asoA-2c6wB:undetectable;3asoJ-2c6wB:undetectable","3asoA-2c6wB:21.23;3asoJ-2c6wB:8.29"],["3DL9_A_V2HA602_1","CYTOCHROME P450 2R1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ASN B 365;ALA B 347;LEU B 327;GLY B 598;THR B 371","None","1.26A","3dl9A-2c6wB:undetectable","3dl9A-2c6wB:19.92"],["3HLW_A_CE3A301_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"LYS B 373;SER B 428;ASN B 430;THR B 543;LYS B 557;GLY B 559","None; CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.67A","3hlwA-2c6wB:16.8","3hlwA-2c6wB:23.08"],["3HLW_B_CE3B302_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 428;ASN B 430;THR B 543;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.50A","3hlwB-2c6wB:17.0","3hlwB-2c6wB:23.08"],["3NY4_A_SMXA308_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.73A","3ny4A-2c6wB:16.5","3ny4A-2c6wB:21.19"],["3NY4_A_SMXA308_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.71A","3ny4A-2c6wB:16.5","3ny4A-2c6wB:21.19"],["3Q07_A_WPPA300_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"LYS B 373;SER B 428;ASN B 430;LYS B 557;GLY B 559","None; CL B 704 (-3.4A);None;None; CL B 704 ( 4.0A)","0.63A","3q07A-2c6wB:16.8","3q07A-2c6wB:23.08"],["3SH8_A_CEDA1_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;ASN B 430;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A);None;None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.67A","3sh8A-2c6wB:16.6","3sh8A-2c6wB:23.56"],["3WG7_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.99A","3wg7A-2c6wB:undetectable;3wg7J-2c6wB:undetectable","3wg7A-2c6wB:21.23;3wg7J-2c6wB:8.29"],["4E0F_A_RBFA301_1","RIBOFLAVIN SYNTHASE SUBUNIT ALPHA","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"SER B 389;VAL B 394;LEU B 421;THR B 390;ALA B 424","None","1.23A","4e0fA-2c6wB:undetectable","4e0fA-2c6wB:17.74"],["4EUZ_A_MEMA401_1","CARBAPENEM-HYDROLIZING BETA-LACTAMASE SFC-1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",8,"LYS B 373;SER B 428;ASN B 430;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560","None; CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.93A","4euzA-2c6wB:16.3","4euzA-2c6wB:22.78"],["4FH2_A_0RNA303_1","BETA-LACTAMASE SHV-1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"SER B 428;ASN B 430;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.4A);None;None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.65A","4fh2A-2c6wB:16.0","4fh2A-2c6wB:19.64"],["4N9K_A_CEDA301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;ASN B 430;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A);None;None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.65A","4n9kA-2c6wB:16.6","4n9kA-2c6wB:23.56"],["4N9K_B_CEDB301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;ASN B 430;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A);None;None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.63A","4n9kB-2c6wB:16.6","4n9kB-2c6wB:23.56"],["4NJK_A_SAMA302_0","7-CARBOXY-7-DEAZAGUANINE SYNTHASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"THR B 332;GLU B 481;ASN B 274;VAL B 279;GLN B 282","None","1.34A","4njkA-2c6wB:undetectable","4njkA-2c6wB:20.60"],["4PM5_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 428;ASN B 430;THR B 543;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.69A","4pm5A-2c6wB:17.0","4pm5A-2c6wB:22.81"],["4PM7_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"LYS B 373;SER B 428;ASN B 430;THR B 543;LYS B 557;GLY B 559","None; CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.84A","4pm7A-2c6wB:17.1","4pm7A-2c6wB:22.81"],["4PM9_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 428;ASN B 430;THR B 543;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.71A","4pm9A-2c6wB:17.1","4pm9A-2c6wB:22.81"],["4QVN_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ALA B 489;THR B 495;ALA B 522;GLY B 339;ALA B 485","None","1.16A","4qvnK-2c6wB:undetectable;4qvnL-2c6wB:undetectable","4qvnK-2c6wB:19.90;4qvnL-2c6wB:18.59"],["4QVN_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ALA B 489;THR B 495;ALA B 522;GLY B 339;ALA B 485","None","1.16A","4qvnY-2c6wB:undetectable;4qvnZ-2c6wB:undetectable","4qvnY-2c6wB:19.90;4qvnZ-2c6wB:18.59"],["4QVQ_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ALA B 489;THR B 495;ALA B 522;GLY B 339;ALA B 485","None","1.16A","4qvqK-2c6wB:undetectable;4qvqL-2c6wB:undetectable","4qvqK-2c6wB:18.86;4qvqL-2c6wB:18.59"],["4QVQ_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ALA B 489;THR B 495;ALA B 522;GLY B 339;ALA B 485","None","1.16A","4qvqY-2c6wB:undetectable;4qvqZ-2c6wB:undetectable","4qvqY-2c6wB:18.86;4qvqZ-2c6wB:18.59"],["5GHZ_A_CEDA301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;ASN B 430;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A);None;None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.66A","5ghzA-2c6wB:16.6","5ghzA-2c6wB:23.56"],["5GHZ_B_CEDB301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;ASN B 430;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A);None;None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.65A","5ghzB-2c6wB:16.6","5ghzB-2c6wB:23.56"],["5IY5_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.91A","5iy5N-2c6wB:undetectable;5iy5W-2c6wB:undetectable","5iy5N-2c6wB:21.23;5iy5W-2c6wB:8.07"],["5L5Z_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ALA B 489;THR B 495;ALA B 522;GLY B 339;ALA B 485","None","1.03A","5l5zK-2c6wB:undetectable;5l5zL-2c6wB:undetectable","5l5zK-2c6wB:20.49;5l5zL-2c6wB:18.59"],["5L5Z_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"ALA B 489;THR B 495;ALA B 522;GLY B 339;ALA B 485","None","1.03A","5l5zY-2c6wB:undetectable;5l5zZ-2c6wB:undetectable","5l5zY-2c6wB:20.49;5l5zZ-2c6wB:18.59"],["5LAK_I_BEZI1_0","3CL PROTEASE;BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",3,"SER B 462;TYR B 461;TYR B 401","None","0.84A","5lakA-2c6wB:undetectable;5lakI-2c6wB:undetectable","5lakA-2c6wB:22.95;5lakI-2c6wB:25.00"],["5LAK_J_BEZJ1_0","3CL PROTEASE;BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",3,"SER B 462;TYR B 461;TYR B 401","None","0.85A","5lakC-2c6wB:undetectable;5lakJ-2c6wB:undetectable","5lakC-2c6wB:22.95;5lakJ-2c6wB:25.00"],["5OJ0_A_9WTA801_0","PENICILLIN-BINDING PROTEIN 2X","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"ARG B 413;SER B 428;ASN B 430;THR B 543;GLY B 559;THR B 560","None; CL B 704 (-3.4A);None; CL B 704 ( 4.8A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","1.14A","5oj0A-2c6wB:26.5","5oj0A-2c6wB:21.60"],["5OJ0_A_9WTA801_0","PENICILLIN-BINDING PROTEIN 2X","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"TRP B 411;SER B 428;ASN B 430;GLY B 559;THR B 560","None; CL B 704 (-3.4A);None; CL B 704 ( 4.0A); CL B 704 ( 4.8A)","1.24A","5oj0A-2c6wB:26.5","5oj0A-2c6wB:21.60"],["5W97_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.80A","5w97J-2c6wB:undetectable","5w97J-2c6wB:8.29"],["5WAU_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.92A","5wauJ-2c6wB:undetectable","5wauJ-2c6wB:8.29"],["5X1B_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.18A","5x1bW-2c6wB:undetectable","5x1bW-2c6wB:8.29"],["5X1F_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","0.89A","5x1fW-2c6wB:undetectable","5x1fW-2c6wB:8.29"],["5Z86_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"ARG B 619;MET B 621;THR B 623;LEU B 625","None","1.29A","5z86J-2c6wB:undetectable","5z86J-2c6wB:8.29"],["5ZMQ_K_PACK1_0","SERINE PROTEASE NS3;PEPTIDE PAC-DLY-DLY-DAR","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",3,"ALA B 343;VAL B 279;TYR B 501","None","0.71A","5zmqH-2c6wB:undetectable","5zmqH-2c6wB:20.31"],["6B5Y_B_9F2B400_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.73A","6b5yB-2c6wB:6.5","6b5yB-2c6wB:12.46"],["6B5Y_B_9F2B400_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.78A","6b5yB-2c6wB:6.5","6b5yB-2c6wB:12.46"],["6B5Y_D_9F2D400_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"SER B 370;SER B 428;THR B 543;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A); CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.45A","6b5yD-2c6wB:16.6","6b5yD-2c6wB:12.46"],["6B68_B_9F2B301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A)","0.59A","6b68B-2c6wB:16.5","6b68B-2c6wB:12.46"],["6B68_B_9F2B301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.66A","6b68B-2c6wB:16.5","6b68B-2c6wB:12.46"],["6B68_D_9F2D400_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"SER B 370;SER B 428;THR B 543;LYS B 557;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.68A","6b68D-2c6wB:16.5","6b68D-2c6wB:12.46"],["6B68_D_9F2D400_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"SER B 428;THR B 543;LYS B 557;GLY B 559;THR B 560"," CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.69A","6b68D-2c6wB:16.5","6b68D-2c6wB:12.46"],["6B69_B_9F2B301_1","BETA-LACTAMASE;BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",7,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.72A","6b69A-2c6wB:16.5;6b69B-2c6wB:16.5","6b69A-2c6wB:12.46;6b69B-2c6wB:12.46"],["6B69_D_9F2D301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",7,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.72A","6b69D-2c6wB:6.8","6b69D-2c6wB:12.46"],["6B6A_B_9F2B301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",7,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.77A","6b6aB-2c6wB:16.6","6b6aB-2c6wB:12.46"],["6B6A_D_9F2D301_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",6,"SER B 370;SER B 428;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.5A); CL B 704 (-3.4A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.80A","6b6aD-2c6wB:16.6","6b6aD-2c6wB:12.46"],["6B6D_A_9F2A302_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",7,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.86A","6b6dA-2c6wB:16.5","6b6dA-2c6wB:12.46"],["6B6E_A_9F2A302_1","BETA-LACTAMASE","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",7,"SER B 370;SER B 428;THR B 543;LYS B 557;THR B 558;GLY B 559;THR B 560"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 (-4.5A); CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.75A","6b6eA-2c6wB:16.7","6b6eA-2c6wB:12.46"],["6C79_A_CE3A301_1","BETA-LACTAMASE TOHO-1","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"SER B 428;ASN B 430;THR B 543;LYS B 557;GLY B 559"," CL B 704 (-3.4A);None; CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.49A","6c79A-2c6wB:16.8","6c79A-2c6wB:15.89"],["6H7L_B_Y00B405_0","BETA-1 ADRENERGIC RECEPTOR","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",5,"VAL B 298;SER B 480;SER B 479;ASN B 359;VAL B 279","None","1.42A","6h7lB-2c6wB:undetectable","6h7lB-2c6wB:10.30"],["6NKN_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2c6w","PENICILLIN-BINDING PROTEIN 1A","Streptococcus pneumoniae",4,"TYR B 618;ARG B 619;MET B 622;THR B 623","None","1.14A","6nknJ-2c6wB:undetectable","6nknJ-2c6wB:8.29"]]