SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		5 / 10 TYR B  95
ALA A  10
ALA A  12
GLU A  23
ALA A  11
 None
 1.29A 2r2vC-2c7lB:
undetectable
2r2vF-2c7lB:
undetectable
2r2vG-2c7lB:
undetectable		 2r2vC-2c7lB:
16.67
2r2vF-2c7lB:
16.67
2r2vG-2c7lB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		5 / 11 LEU B  38
LEU B 160
VAL B  97
LEU A  24
ILE B  51
 CYC  B1174 (-3.6A)
None
None
CYC  B1174 (-4.7A)
None
 1.11A 2uxoB-2c7lB:
0.0		 2uxoB-2c7lB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		5 / 10 THR B 122
PRO B 123
GLY B 124
LEU B  86
GLY B 130
 CYC  B1173 (-3.5A)
None
None
CYC  B1173 (-4.1A)
None
 1.08A 2vl2A-2c7lB:
undetectable
2vl2C-2c7lB:
undetectable		 2vl2A-2c7lB:
22.06
2vl2C-2c7lB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		4 / 8 ASN B  25
GLU B  23
ILE B  24
ASN A  46
 None
 0.93A 4d33A-2c7lB:
undetectable		 4d33A-2c7lB:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		4 / 7 ASN B  25
GLU B  23
ILE B  24
ASN A  46
 None
 0.94A 4d33B-2c7lB:
undetectable		 4d33B-2c7lB:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		4 / 8 ASN B  25
GLU B  23
ILE B  24
ASN A  46
 None
 0.93A 4d39A-2c7lB:
undetectable		 4d39A-2c7lB:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		4 / 7 ASN B  25
GLU B  23
ILE B  24
ASN A  46
 None
 0.97A 4d39B-2c7lB:
undetectable		 4d39B-2c7lB:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		5 / 11 LEU B  44
ALA B 137
GLY B 130
ILE B 131
ILE B  51
 None
 0.98A 4dqeA-2c7lB:
undetectable		 4dqeA-2c7lB:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ILE A  88
HIS A  58
ALA A 132
TYR A 129
 None
None
None
BLA  A1163 (-3.9A)
 0.76A 4g77A-2c7lA:
undetectable		 4g77A-2c7lA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ILE A  88
LEU A  92
ALA A 132
TYR A 129
 None
None
None
BLA  A1163 (-3.9A)
 0.79A 4g77A-2c7lA:
undetectable		 4g77A-2c7lA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		4 / 7 ALA A   8
PRO A   4
LEU B  98
LEU A  19
 None
 1.02A 4iomA-2c7lA:
undetectable		 4iomA-2c7lA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		5 / 11 LEU B  44
ALA B 137
GLY B 130
ILE B 131
ILE B  51
 None
 0.99A 4njtA-2c7lB:
undetectable		 4njtA-2c7lB:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		5 / 11 LEU B  44
ALA B 137
GLY B 130
ILE B 131
ILE B  51
 None
 0.96A 4njtC-2c7lB:
undetectable		 4njtC-2c7lB:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.29A 4v2yA-2c7lB:
undetectable		 4v2yA-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.30A 4v2yB-2c7lB:
undetectable		 4v2yB-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.31A 4v2zA-2c7lB:
undetectable		 4v2zA-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 8 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.33A 4v2zB-2c7lB:
undetectable		 4v2zB-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.31A 4v30A-2c7lB:
undetectable		 4v30A-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.34A 5amiA-2c7lB:
undetectable		 5amiA-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 8 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.34A 5amiB-2c7lB:
undetectable		 5amiB-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.32A 5amjA-2c7lB:
undetectable		 5amjA-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.33A 5amjB-2c7lB:
undetectable		 5amjB-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 8 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.39A 5amkA-2c7lB:
undetectable		 5amkA-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.26A 5amkB-2c7lB:
undetectable		 5amkB-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 4 TYR A  18
ASN B  47
SER B  50
SER B  49
 None
 0.98A 5gsnC-2c7lA:
undetectable		 5gsnC-2c7lA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		5 / 12 LEU B  59
ALA B  55
MET B 105
ILE B 131
LEU B 160
 None
 1.30A 5ljbA-2c7lB:
undetectable		 5ljbA-2c7lB:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.36A 5oh3A-2c7lB:
undetectable		 5oh3A-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 2c7l PHYCOERYTHROCYANIN
BETA CHAIN
(Mastigocladus
laminosus) 		4 / 7 ASN B  68
PRO B  69
PHE B  74
TYR B  56
 None
 1.34A 5oh3B-2c7lB:
undetectable		 5oh3B-2c7lB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 12 ILE A 158
ASN A 139
ALA A  43
ALA A 150
ALA A 147
 None
 1.06A 5zw4A-2c7lA:
undetectable		 5zw4A-2c7lA:
21.37