SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		3 / 3 ASP A 119
LEU A  46
LEU A 122
 None
 0.67A 1ikeA-2c8sA:
undetectable		 1ikeA-2c8sA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		3 / 3 ASP A 119
LEU A  46
LEU A 122
 None
 0.77A 1np1B-2c8sA:
undetectable		 1np1B-2c8sA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		3 / 3 HIS A 130
SER A  59
GLU A  58
 None
 0.88A 3s8pA-2c8sA:
undetectable		 3s8pA-2c8sA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		4 / 6 PHE A  98
ASN A  45
ALA A  35
THR A  33
 None
 0.97A 3t3sB-2c8sA:
undetectable		 3t3sB-2c8sA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		4 / 7 PHE A  98
ASN A  45
ALA A  35
THR A  33
 None
 0.93A 3t3sC-2c8sA:
undetectable		 3t3sC-2c8sA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		4 / 8 PHE A  98
ASN A  45
ALA A  35
THR A  33
 None
 0.92A 3t3sD-2c8sA:
undetectable		 3t3sD-2c8sA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2c8s CYTOCHROME C-L
(Methylobacterium
extorquens) 		4 / 6 PHE A  98
ASN A  45
ALA A  35
THR A  33
 None
 1.05A 4ejgD-2c8sA:
undetectable		 4ejgD-2c8sA:
19.62