SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		5 / 11 GLN A 141
ALA A 142
ALA A 145
ALA A 146
LEU A 101
 None
 1.10A 4j6cA-2c94A:
undetectable		 4j6cA-2c94A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		5 / 10 GLN A 141
ALA A 142
ALA A 145
ALA A 146
LEU A 101
 None
 1.12A 4j6cB-2c94A:
undetectable		 4j6cB-2c94A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		5 / 12 GLN A 141
ALA A 142
ALA A 145
ALA A 146
LEU A 101
 None
 1.11A 4jbtA-2c94A:
undetectable		 4jbtA-2c94A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		5 / 11 GLN A 141
ALA A 142
ALA A 145
ALA A 146
LEU A 101
 None
 1.11A 4jbtB-2c94A:
undetectable		 4jbtB-2c94A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		3 / 3 SER A  25
ALA A  78
VAL A  77
 TSF  A 701 (-3.1A)
None
None
 0.68A 4o2bC-2c94A:
2.2		 4o2bC-2c94A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		4 / 7 ALA A  24
GLY A  38
ALA A  39
THR A 143
 None
K  A1162 (-3.8A)
None
None
 0.77A 4r1zB-2c94A:
undetectable		 4r1zB-2c94A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  79
VAL A  97
LEU A 101
ILE A  62
 None
 0.79A 4r38A-2c94A:
undetectable		 4r38A-2c94A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  79
VAL A  97
LEU A 101
ILE A  62
 None
 0.79A 4r38D-2c94A:
undetectable		 4r38D-2c94A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
(Mycobacterium
tuberculosis) 		3 / 3 SER A  25
ALA A  78
VAL A  77
 TSF  A 701 (-3.1A)
None
None
 0.55A 5xiwC-2c94A:
undetectable		 5xiwC-2c94A:
17.09