SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 6 ARG A 239
ILE A 209
GLY A 210
HIS A 187
 None
 0.90A 1wmqA-2c9aA:
undetectable		 1wmqA-2c9aA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 6 ARG A 239
ILE A 209
GLY A 210
HIS A 187
 None
 0.90A 1wmqB-2c9aA:
undetectable		 1wmqB-2c9aA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 6 ARG A 239
ILE A 209
GLY A 210
HIS A 187
 None
 0.89A 1wpuA-2c9aA:
undetectable		 1wpuA-2c9aA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 6 ARG A 239
ILE A 209
GLY A 210
HIS A 187
 None
 0.89A 1wpuB-2c9aA:
undetectable		 1wpuB-2c9aA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 6 ARG A 239
ILE A 209
GLY A 210
HIS A 187
 None
 0.87A 1wrqA-2c9aA:
undetectable		 1wrqA-2c9aA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 6 ARG A 239
ILE A 209
GLY A 210
HIS A 187
 None
 0.89A 1wrqB-2c9aA:
undetectable		 1wrqB-2c9aA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		4 / 8 LEU A 276
VAL A 194
ALA A 228
LEU A 220
 None
 0.81A 4qrcA-2c9aA:
undetectable		 4qrcA-2c9aA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		5 / 12 GLY A  37
SER A  39
LEU A  85
VAL A 177
LEU A  89
 None
 0.93A 5kpcA-2c9aA:
undetectable		 5kpcA-2c9aA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		3 / 3 SER A  39
TYR A  38
TYR A  33
 None
 0.86A 5lakA-2c9aA:
undetectable
5lakI-2c9aA:
undetectable		 5lakA-2c9aA:
21.15
5lakI-2c9aA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		3 / 3 SER A  39
TYR A  38
TYR A  33
 None
 0.81A 5lakC-2c9aA:
undetectable
5lakJ-2c9aA:
undetectable		 5lakC-2c9aA:
21.15
5lakJ-2c9aA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 2c9a RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU
(Homo
sapiens) 		3 / 3 SER A 107
LYS A 106
SER A 105
 None
 0.74A 6az3P-2c9aA:
undetectable		 6az3P-2c9aA:
16.59