SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2c9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 8 PHE A  38
LEU A 196
THR A  42
VAL A  12
 CRQ  A  62 ( 3.6A)
CRQ  A  62 ( 4.2A)
None
None
 1.09A 1dz9A-2c9jA:
undetectable		 1dz9A-2c9jA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		5 / 11 VAL A  12
GLY A  27
LEU A  40
GLY A 116
GLU A 212
 None
None
CRQ  A  62 ( 4.6A)
None
CRQ  A  62 ( 3.4A)
 1.38A 1iolA-2c9jA:
undetectable		 1iolA-2c9jA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 8 PHE A  38
LEU A 196
THR A  42
VAL A  12
 CRQ  A  62 ( 3.6A)
CRQ  A  62 ( 4.2A)
None
None
 1.10A 1uyuA-2c9jA:
undetectable		 1uyuA-2c9jA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 8 PHE A  38
LEU A 196
THR A  42
VAL A  12
 CRQ  A  62 ( 3.6A)
CRQ  A  62 ( 4.2A)
None
None
 1.07A 1uyuB-2c9jA:
undetectable		 1uyuB-2c9jA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		5 / 11 ILE A  75
ILE A 192
THR A 145
PRO A 187
LEU A 153
 None
 1.21A 3a51A-2c9jA:
undetectable		 3a51A-2c9jA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		5 / 12 ILE A  75
ILE A 192
THR A 145
PRO A 187
LEU A 153
 None
 1.15A 3a51C-2c9jA:
undetectable		 3a51C-2c9jA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 8 PHE A  79
VAL A 152
LEU A 186
PRO A 187
 None
 1.14A 3jq7C-2c9jA:
undetectable		 3jq7C-2c9jA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 7 GLY A  27
PHE A  79
PHE A  65
GLY A  30
 None
None
CRQ  A  62 ( 3.7A)
None
 0.97A 3ko0M-2c9jA:
undetectable
3ko0P-2c9jA:
undetectable		 3ko0M-2c9jA:
20.90
3ko0P-2c9jA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 7 PHE A  65
GLY A  30
GLY A  27
PHE A  79
 CRQ  A  62 ( 3.7A)
None
None
None
 0.91A 3ko0M-2c9jA:
undetectable
3ko0P-2c9jA:
undetectable		 3ko0M-2c9jA:
20.90
3ko0P-2c9jA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 5 LEU A  40
ARG A  66
ILE A 107
PHE A  65
 CRQ  A  62 ( 4.6A)
CRQ  A  62 ( 4.0A)
None
CRQ  A  62 ( 3.7A)
 1.23A 3ln1D-2c9jA:
0.0		 3ln1D-2c9jA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2c9j GREEN FLUORESCENT
PROTEIN FP512
(Cerianthus
membranaceus) 		4 / 6 PHE A  87
ALA A  86
PRO A  33
LEU A 114
 None
 1.12A 4dtzB-2c9jA:
undetectable		 4dtzB-2c9jA:
19.74