SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cas'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		5 / 12 LEU A 482
ILE A 357
ALA A 358
THR A 278
THR A 406
 None
 1.07A 1cbsA-2casA:
undetectable		 1cbsA-2casA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 8 GLY A 264
THR A 263
GLY A 531
GLN A 143
 None
 0.84A 1jr1B-2casA:
undetectable		 1jr1B-2casA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.40A 1tt0A-2casA:
0.0		 1tt0A-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.38A 1tt0B-2casA:
0.0		 1tt0B-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.42A 1tt0C-2casA:
0.0		 1tt0C-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.40A 1tt0D-2casA:
0.0		 1tt0D-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		3 / 3 ALA A 188
THR A 206
PHE A 185
 None
 0.74A 2c6nB-2casA:
undetectable		 2c6nB-2casA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		3 / 3 ARG A 209
ASP A 100
ASP A  88
 None
 0.78A 2ejtA-2casA:
undetectable		 2ejtA-2casA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		5 / 12 LEU A 482
ILE A 357
ALA A 358
THR A 278
THR A 406
 None
 1.05A 2g78A-2casA:
undetectable		 2g78A-2casA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.39A 3lskB-2casA:
undetectable		 3lskB-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_C_ACTC901_0
(PYRANOSE 2-OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 5 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.44A 3lskC-2casA:
0.0		 3lskC-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 GLN A 468
PHE A 185
HIS A 483
ASN A 485
 None
 1.44A 3lskD-2casA:
undetectable		 3lskD-2casA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 6 PHE A 185
ASN A 485
ALA A 189
THR A 194
 None
 1.16A 3t3sB-2casA:
undetectable		 3t3sB-2casA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 8 ALA A 486
ASN A 485
ALA A 189
THR A 194
 None
 0.69A 3t3sD-2casA:
undetectable		 3t3sD-2casA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 8 ALA A 486
ASN A 485
ALA A 189
THR A 194
 None
 0.81A 3t3sF-2casA:
undetectable		 3t3sF-2casA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		5 / 12 GLY A 496
LEU A 498
ILE A 246
ASN A 180
VAL A 250
 None
 1.11A 4fr0A-2casA:
undetectable		 4fr0A-2casA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 8 LYS A  52
LEU A  54
THR A  62
VAL A 534
 None
 0.76A 4iizB-2casA:
undetectable		 4iizB-2casA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 8 LYS A  52
LEU A  54
THR A  62
VAL A 534
 None
 0.84A 4ik6B-2casA:
1.5		 4ik6B-2casA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 5 ALA A 114
VAL A 112
PHE A 141
ILE A 145
 None
 1.01A 5of1A-2casA:
undetectable		 5of1A-2casA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 5 ALA A 114
VAL A 112
PHE A 141
ILE A 145
 None
 1.01A 5of1B-2casA:
2.8		 5of1B-2casA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		5 / 9 VAL A  59
VAL A 130
MET A 133
ASP A 125
GLY A 124
 None
 1.40A 5zniA-2casA:
undetectable		 5zniA-2casA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2
(Carnivore
protoparvovirus
1) 		4 / 8 GLY A 381
GLN A 386
SER A 192
PHE A 197
 None
 1.17A 6eqpA-2casA:
undetectable		 6eqpA-2casA:
8.95