SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		4 / 8 THR A 169
PRO A 170
GLY A 171
ARG A 198
 None
 0.89A 1oc3A-2cc3A:
undetectable		 1oc3A-2cc3A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		4 / 6 ASN A 166
SER A 165
ALA A 164
HIS A 162
 None
 1.18A 3aruA-2cc3A:
undetectable		 3aruA-2cc3A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		3 / 3 TYR A 112
TYR A 142
GLY A 153
 None
 0.55A 3eteB-2cc3A:
undetectable
3eteD-2cc3A:
undetectable
3eteF-2cc3A:
undetectable		 3eteB-2cc3A:
15.37
3eteD-2cc3A:
15.37
3eteF-2cc3A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		5 / 11 VAL A 160
TYR A 112
TYR A 136
TYR A 222
TYR A 105
 None
 1.20A 3qxyB-2cc3A:
undetectable
3qxyQ-2cc3A:
undetectable		 3qxyB-2cc3A:
15.26
3qxyQ-2cc3A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		5 / 11 VAL A 160
TYR A 112
TYR A 136
TYR A 222
TYR A 105
 None
 1.25A 3rc0A-2cc3A:
undetectable		 3rc0A-2cc3A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		4 / 8 ASN A 213
PRO A 214
PHE A 127
TYR A 119
 None
None
None
MPD  A1232 (-4.5A)
 1.47A 5amkA-2cc3A:
undetectable		 5amkA-2cc3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2cc3 PROTEIN VIRB8
(Agrobacterium
tumefaciens) 		4 / 6 LYS A 201
ARG A 210
SER A 204
LEU A 205
 None
 1.23A 5bphD-2cc3A:
undetectable		 5bphD-2cc3A:
19.34