SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ccm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 8 ILE A  30
ALA A  73
VAL A  81
MET A  89
 None
 0.63A 1a29A-2ccmA:
11.0		 1a29A-2ccmA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 6 ASN A 183
ILE A  14
SER A   7
ASN A 176
 None
 1.21A 1h7xA-2ccmA:
undetectable		 1h7xA-2ccmA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 6 ASN A 183
ILE A  14
SER A   7
ASN A 176
 None
 1.19A 1h7xB-2ccmA:
undetectable		 1h7xB-2ccmA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 6 ASN A 183
ILE A  14
SER A   7
ASN A 176
 None
 1.20A 1h7xC-2ccmA:
undetectable		 1h7xC-2ccmA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 6 ASN A 183
ILE A  14
SER A   7
ASN A 176
 None
 1.21A 1h7xD-2ccmA:
undetectable		 1h7xD-2ccmA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 7 TRP A 169
TYR A 110
ASN A 118
TYR A 135
 None
 1.32A 1kiaC-2ccmA:
undetectable		 1kiaC-2ccmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 7 TRP A 169
TYR A 110
ASN A 118
TYR A 135
 None
 1.32A 1kiaD-2ccmA:
undetectable		 1kiaD-2ccmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 7 TRP A 169
TYR A 110
ASN A 118
TYR A 135
 None
 1.31A 1nbhB-2ccmA:
undetectable		 1nbhB-2ccmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 7 TRP A 169
TYR A 110
ASN A 118
TYR A 135
 None
 1.31A 1nbhD-2ccmA:
undetectable		 1nbhD-2ccmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		5 / 11 LEU A 107
TYR A  22
VAL A  17
ILE A  14
LEU A   6
 None
 1.18A 4lhmA-2ccmA:
undetectable		 4lhmA-2ccmA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_A_TFPA203_1
(CALMODULIN)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 8 ILE A  30
ALA A  73
VAL A  81
MET A  89
 None
 0.57A 4rjdA-2ccmA:
4.8		 4rjdA-2ccmA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		3 / 3 PHE A  35
ILE A  65
ASP A 116
 None
 0.76A 5cswB-2ccmA:
undetectable		 5cswB-2ccmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2ccm CALEXCITIN
(Doryteuthis
pealeii) 		4 / 8 PHE A 186
PHE A 165
VAL A 134
TYR A 131
 None
 0.97A 6huoC-2ccmA:
undetectable
6huoD-2ccmA:
undetectable		 6huoC-2ccmA:
16.67
6huoD-2ccmA:
18.44