SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ccz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2ccz	PRIMOSOMAL REPLICATION PROTEIN N (Escherichia coli)	3 / 3	SER A 55 GLY A 56 GLN A 60	None	0.64A	3v4tH-2cczA: undetectable	3v4tH-2cczA: 16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5O_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	2ccz	PRIMOSOMAL REPLICATION PROTEIN N (Escherichia coli)	4 / 7	CYH A 27 ILE A 53 PRO A 15 ILE A 66	None	1.08A	4w5oA-2cczA: undetectable	4w5oA-2cczA: 9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4E_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	2ccz	PRIMOSOMAL REPLICATION PROTEIN N (Escherichia coli)	4 / 7	CYH A 27 ILE A 53 PRO A 15 ILE A 66	None	1.05A	4z4eA-2cczA: undetectable	4z4eA-2cczA: 9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZWR_A_9KLA402_0 (EST-Y29)	2ccz	PRIMOSOMAL REPLICATION PROTEIN N (Escherichia coli)	5 / 12	PHE A 29 ILE A 72 LEU A 31 ALA A 94 LEU A 92	None	1.15A	5zwrA-2cczA: undetectable	5zwrA-2cczA: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZWR_B_9KLB402_0 (EST-Y29)	2ccz	PRIMOSOMAL REPLICATION PROTEIN N (Escherichia coli)	5 / 12	PHE A 29 ILE A 72 LEU A 31 ALA A 94 LEU A 92	None	1.12A	5zwrB-2cczA: undetectable	5zwrB-2cczA: 12.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3V4T_H_ACTH502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2ccz","PRIMOSOMAL REPLICATION PROTEIN N","Escherichia coli",3,"SER A  55;GLY A  56;GLN A  60","None","0.64A","3v4tH-2cczA:undetectable","3v4tH-2cczA:16.23"],["4W5O_A_IPHA904_0","PROTEIN ARGONAUTE-2","2ccz","PRIMOSOMAL REPLICATION PROTEIN N","Escherichia coli",4,"CYH A  27;ILE A  53;PRO A  15;ILE A  66","None","1.08A","4w5oA-2cczA:undetectable","4w5oA-2cczA:9.50"],["4Z4E_A_IPHA904_0","PROTEIN ARGONAUTE-2","2ccz","PRIMOSOMAL REPLICATION PROTEIN N","Escherichia coli",4,"CYH A  27;ILE A  53;PRO A  15;ILE A  66","None","1.05A","4z4eA-2cczA:undetectable","4z4eA-2cczA:9.50"],["5ZWR_A_9KLA402_0","EST-Y29","2ccz","PRIMOSOMAL REPLICATION PROTEIN N","Escherichia coli",5,"PHE A  29;ILE A  72;LEU A  31;ALA A  94;LEU A  92","None","1.15A","5zwrA-2cczA:undetectable","5zwrA-2cczA:12.53"],["5ZWR_B_9KLB402_0","EST-Y29","2ccz","PRIMOSOMAL REPLICATION PROTEIN N","Escherichia coli",5,"PHE A  29;ILE A  72;LEU A  31;ALA A  94;LEU A  92","None","1.12A","5zwrB-2cczA:undetectable","5zwrB-2cczA:12.53"]]