SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2cde INKT-TCR
(Homo
sapiens) 		4 / 5 ARG A  34
MET A  50
THR A  51
LEU A  66
 None
 1.43A 2eimJ-2cdeA:
undetectable		 2eimJ-2cdeA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 2cde INKT-TCR
(Homo
sapiens) 		3 / 3 ASN A  59
ASP A  84
GLN A  81
 None
 0.68A 3eeyC-2cdeA:
undetectable		 3eeyC-2cdeA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 2cde INKT-TCR
(Homo
sapiens) 		3 / 3 ASN A  59
ASP A  84
GLN A  81
 None
 0.71A 3eeyD-2cdeA:
undetectable		 3eeyD-2cdeA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 2cde INKT-TCR
(Homo
sapiens) 		3 / 3 ASN A  59
ASP A  84
GLN A  81
 None
 0.69A 3eeyE-2cdeA:
undetectable		 3eeyE-2cdeA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2cde INKT-TCR
(Homo
sapiens) 		4 / 7 GLN A 109
THR A 108
LEU A  21
THR A  78
 None
 0.98A 4mbsA-2cdeA:
undetectable		 4mbsA-2cdeA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2cde INKT-TCR
(Homo
sapiens) 		4 / 5 ARG A  34
MET A  50
THR A  51
LEU A  66
 None
 1.42A 5wauJ-2cdeA:
undetectable		 5wauJ-2cdeA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2cde INKT-TCR
(Homo
sapiens) 		4 / 7 ALA A  64
THR A  63
TYR A  62
PRO A   8
 None
 0.94A 6cduA-2cdeA:
undetectable
6cduE-2cdeA:
undetectable		 6cduA-2cdeA:
20.31
6cduE-2cdeA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2cde INKT-TCR
(Homo
sapiens) 		4 / 7 PRO A   8
ALA A  64
THR A  63
TYR A  62
 None
 0.92A 6cduH-2cdeA:
undetectable
6cduI-2cdeA:
undetectable		 6cduH-2cdeA:
20.31
6cduI-2cdeA:
20.31