SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 7 PHE A 182
GLY A 217
ILE A 177
GLY A 185
None
0.81A 11gsB-2cdqA:
undetectable
11gsB-2cdqA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 5 LEU A 478
LEU A 332
LEU A 488
LEU A 425
None
0.96A 1yajD-2cdqA:
undetectable
1yajD-2cdqA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 8 LEU A 150
ILE A 154
LEU A 100
ILE A  97
None
0.85A 2azxA-2cdqA:
undetectable
2azxA-2cdqA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 GLU A  78
GLY A  77
ASN A  71
ALA A  80
ALA A 130
None
1.26A 2br4B-2cdqA:
undetectable
2br4B-2cdqA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
6 / 12 SER A  64
LEU A 244
ALA A 299
ILE A 304
ILE A 249
ALA A 237
LYS  A 601 (-3.9A)
None
None
None
None
None
1.45A 2bxcA-2cdqA:
undetectable
2bxcA-2cdqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 ILE A 411
LEU A 384
LEU A 344
VAL A 414
GLU A 407
None
1.17A 2bxfA-2cdqA:
2.0
2bxfA-2cdqA:
21.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
8 / 8 ILE A 370
SER A 371
ASP A 387
TRP A 392
SER A 393
ARG A 394
LEU A 396
GLU A 400
SAM  A1500 (-4.4A)
LYS  A 600 ( 3.3A)
SAM  A1500 (-4.7A)
SAM  A1500 (-3.7A)
SAM  A1500 (-2.6A)
SAM  A1500 (-3.7A)
SAM  A1500 (-4.1A)
SAM  A1500 (-3.8A)
0.00A 2cdqA-2cdqA:
62.0
2cdqA-2cdqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
7 / 7 SER A 371
ASP A 387
TRP A 392
SER A 393
ARG A 394
LEU A 396
GLU A 400
LYS  A 600 ( 3.3A)
SAM  A1500 (-4.7A)
SAM  A1500 (-3.7A)
SAM  A1500 (-2.6A)
SAM  A1500 (-3.7A)
SAM  A1500 (-4.1A)
SAM  A1500 (-3.8A)
0.25A 2cdqB-2cdqA:
59.7
2cdqB-2cdqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 4 ASP A 180
ASP A 141
ASP A 186
GLY A 217
None
1.19A 2igtC-2cdqA:
2.8
2igtC-2cdqA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 7 PHE A 482
LEU A 436
ALA A 439
PHE A 464
None
0.89A 2vcvG-2cdqA:
undetectable
2vcvG-2cdqA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 8 ILE A  97
HIS A 101
LEU A 122
GLY A 147
None
0.89A 2vdbA-2cdqA:
undetectable
2vdbA-2cdqA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 9 ILE A 335
ALA A 471
VAL A 475
GLU A 472
None
0.83A 2vufA-2cdqA:
3.0
2vufA-2cdqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 7 VAL A 308
ALA A 284
VAL A 290
GLY A 257
THR A 319
None
1.36A 2xrzB-2cdqA:
2.1
2xrzB-2cdqA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 THR A 178
ILE A 187
GLY A 229
THR A  70
LEU A  73
None
None
None
LYS  A 601 (-3.5A)
None
1.03A 2y7hB-2cdqA:
undetectable
2y7hB-2cdqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 THR A 178
ILE A 187
GLY A 229
THR A  70
LEU A  73
None
None
None
LYS  A 601 (-3.5A)
None
1.03A 2y7hC-2cdqA:
undetectable
2y7hC-2cdqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 ILE A 335
LEU A 332
ILE A 423
VAL A 448
PHE A 440
None
1.13A 2ygpA-2cdqA:
undetectable
2ygpA-2cdqA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 4 GLY A 147
GLU A 148
ASP A 170
TYR A 118
None
LYS  A 601 (-3.5A)
None
None
1.44A 2yvlC-2cdqA:
undetectable
2yvlC-2cdqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 ILE A 129
LEU A 135
ILE A  91
ALA A  88
LEU A 122
None
1.10A 3a50D-2cdqA:
undetectable
3a50D-2cdqA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 11 GLY A 214
THR A 226
THR A 227
ARG A 153
GLY A 147
None
1.43A 3abmA-2cdqA:
0.8
3abmB-2cdqA:
0.0
3abmT-2cdqA:
0.0
3abmA-2cdqA:
22.15
3abmB-2cdqA:
20.65
3abmT-2cdqA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 10 ARG A 153
GLY A 147
GLY A 214
THR A 226
THR A 227
None
1.45A 3abmG-2cdqA:
0.0
3abmN-2cdqA:
1.0
3abmO-2cdqA:
0.0
3abmG-2cdqA:
9.92
3abmN-2cdqA:
22.15
3abmO-2cdqA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 11 GLY A 214
THR A 226
THR A 227
ARG A 153
GLY A 147
None
1.42A 3ag1A-2cdqA:
0.9
3ag1B-2cdqA:
0.0
3ag1T-2cdqA:
0.0
3ag1A-2cdqA:
22.15
3ag1B-2cdqA:
20.65
3ag1T-2cdqA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 ILE A 304
GLY A 241
VAL A 195
GLY A 302
THR A 238
None
1.01A 3bwcA-2cdqA:
2.3
3bwcA-2cdqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 6 THR A 238
LEU A 235
GLY A 231
ALA A 299
PRO A 298
None
1.20A 3huoA-2cdqA:
undetectable
3huoA-2cdqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 6 THR A 238
LEU A 235
GLY A 232
ALA A 299
PRO A 298
None
None
LYS  A 601 (-3.6A)
None
None
1.05A 3huoA-2cdqA:
undetectable
3huoA-2cdqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 GLY A  34
GLY A  67
LEU A 108
VAL A  47
ALA A  48
None
0.99A 3t7vA-2cdqA:
undetectable
3t7vA-2cdqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 8 LEU A 228
THR A 213
LEU A 235
VAL A 212
None
0.83A 4iizB-2cdqA:
undetectable
4iizB-2cdqA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 10 LEU A 246
GLY A 241
VAL A 212
ILE A  61
VAL A  62
None
0.94A 4jx1B-2cdqA:
undetectable
4jx1B-2cdqA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 5 PHE A 483
PRO A 271
VAL A 272
ALA A 269
None
1.33A 4z4dA-2cdqA:
undetectable
4z4dA-2cdqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 5 PHE A 483
PRO A 271
VAL A 272
ALA A 269
None
1.33A 4z4eA-2cdqA:
undetectable
4z4eA-2cdqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 8 GLN A 294
ASP A 181
THR A 178
LEU A 235
None
1.06A 5hwaA-2cdqA:
undetectable
5hwaA-2cdqA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 LEU A 119
ILE A 211
THR A  69
ALA A  65
LEU A  63
None
None
None
LYS  A 601 (-3.9A)
None
1.12A 5ienA-2cdqA:
undetectable
5ienA-2cdqA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 LEU A 119
ILE A 211
THR A  69
ALA A  65
LEU A  63
None
None
None
LYS  A 601 (-3.9A)
None
1.15A 5ienB-2cdqA:
undetectable
5ienB-2cdqA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 10 GLY A 214
THR A 226
THR A 227
ARG A 153
GLY A 147
None
1.36A 5iy5A-2cdqA:
0.8
5iy5B-2cdqA:
0.0
5iy5T-2cdqA:
0.0
5iy5A-2cdqA:
22.15
5iy5B-2cdqA:
20.65
5iy5T-2cdqA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 11 ARG A 153
GLY A 147
GLY A 214
THR A 226
THR A 227
None
1.48A 5w97G-2cdqA:
0.0
5w97a-2cdqA:
0.9
5w97b-2cdqA:
0.0
5w97G-2cdqA:
9.92
5w97a-2cdqA:
22.15
5w97b-2cdqA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 8 PRO A 298
THR A 236
THR A 239
TYR A 192
None
1.35A 5x2sI-2cdqA:
undetectable
5x2sJ-2cdqA:
undetectable
5x2sK-2cdqA:
undetectable
5x2sI-2cdqA:
17.52
5x2sJ-2cdqA:
16.18
5x2sK-2cdqA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 5 PRO A 210
VAL A  60
GLY A 217
VAL A 195
None
1.12A 6ak3B-2cdqA:
undetectable
6ak3B-2cdqA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 GLY A 257
GLY A 318
ASN A 313
ALA A 316
LEU A 259
None
1.10A 6b3aA-2cdqA:
undetectable
6b3aA-2cdqA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 12 GLY A 257
GLY A 318
ASN A 313
ALA A 316
LEU A 259
None
1.06A 6b3bA-2cdqA:
undetectable
6b3bA-2cdqA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
4 / 7 ILE A  27
VAL A  30
ILE A 240
THR A 236
None
0.96A 6cduF-2cdqA:
undetectable
6cduG-2cdqA:
undetectable
6cduF-2cdqA:
20.39
6cduG-2cdqA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
2cdq ASPARTOKINASE
(Arabidopsis
thaliana)
5 / 10 ARG A 153
GLY A 147
GLY A 214
THR A 226
THR A 227
None
1.50A 6nmpG-2cdqA:
0.0
6nmpN-2cdqA:
0.9
6nmpO-2cdqA:
0.0
6nmpG-2cdqA:
9.92
6nmpN-2cdqA:
22.15
6nmpO-2cdqA:
20.65