SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ce9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		4 / 8 ALA A 673
LEU A 704
HIS A 695
LEU A 694
 None
 0.77A 1ereE-2ce9A:
undetectable		 1ereE-2ce9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		4 / 8 ALA A 673
LEU A 704
HIS A 695
LEU A 694
 None
 0.77A 1ereF-2ce9A:
undetectable		 1ereF-2ce9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 9 VAL A 507
GLY A 503
ALA A 489
ILE A 533
SER A 744
 None
 1.16A 1gtnL-2ce9A:
undetectable
1gtnM-2ce9A:
undetectable		 1gtnL-2ce9A:
10.95
1gtnM-2ce9A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		3 / 3 TRP A 671
TYR A 729
LEU A 694
 None
 1.11A 1kxhA-2ce9A:
undetectable		 1kxhA-2ce9A:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		4 / 4 LEU A 554
VAL A 547
ILE A 546
TRP A 601
 None
 1.28A 1s9qB-2ce9A:
undetectable		 1s9qB-2ce9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 10 VAL A 547
LEU A 545
TRP A 557
SER A 555
GLY A 502
 None
 1.22A 3ls4H-2ce9A:
undetectable		 3ls4H-2ce9A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A 716
VAL A 714
GLU A 738
 None
 0.57A 3v4tA-2ce9A:
undetectable
3v4tD-2ce9A:
undetectable		 3v4tA-2ce9A:
21.60
3v4tD-2ce9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 12 CYH A 577
ALA A 489
GLY A 548
LEU A 570
LEU A 554
 None
 1.15A 4lg1C-2ce9A:
undetectable		 4lg1C-2ce9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A 533
GLY A 503
LEU A 545
LEU A 559
LEU A 524
 None
 1.02A 5nfjB-2ce9A:
undetectable		 5nfjB-2ce9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A 533
GLY A 503
LEU A 545
LEU A 559
LEU A 524
 None
 1.03A 5nfjC-2ce9A:
undetectable		 5nfjC-2ce9A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU A 722
SER A 736
PHE A 734
HIS A 474
 None
 1.04A 5om3A-2ce9A:
undetectable
5om3B-2ce9A:
undetectable		 5om3A-2ce9A:
12.00
5om3B-2ce9A:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 548
GLY A 549
ALA A 551
ILE A 546
LEU A 580
 None
 1.06A 6b3aA-2ce9A:
undetectable		 6b3aA-2ce9A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 548
GLY A 549
ALA A 551
ILE A 546
LEU A 580
 None
 1.06A 6b3bA-2ce9A:
undetectable		 6b3bA-2ce9A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2ce9 TRANSDUCIN-LIKE
ENHANCER PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 480
THR A 501
VAL A 507
SER A 758
VAL A 742
 None
 1.13A 6bzoC-2ce9A:
undetectable		 6bzoC-2ce9A:
15.43