SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cfe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		3 / 3 TYR A  46
GLY A  48
PHE A  65
 None
 0.67A 2m2pB-2cfeA:
undetectable		 2m2pB-2cfeA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 6 PHE A  20
PHE A  34
GLY A  62
GLY A  63
 None
 0.92A 2qr2A-2cfeA:
undetectable
2qr2B-2cfeA:
undetectable		 2qr2A-2cfeA:
21.24
2qr2B-2cfeA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 GLY A  62
GLY A  63
PHE A  20
PHE A  34
 None
 0.85A 2qr2A-2cfeA:
undetectable
2qr2B-2cfeA:
undetectable		 2qr2A-2cfeA:
21.24
2qr2B-2cfeA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 6 PHE A  20
PHE A  34
GLY A  62
GLY A  63
 None
 0.82A 2qx6A-2cfeA:
undetectable
2qx6B-2cfeA:
undetectable		 2qx6A-2cfeA:
21.24
2qx6B-2cfeA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.34A 2y69C-2cfeA:
undetectable
2y69J-2cfeA:
undetectable		 2y69C-2cfeA:
19.17
2y69J-2cfeA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.34A 2y69P-2cfeA:
undetectable
2y69W-2cfeA:
undetectable		 2y69P-2cfeA:
19.17
2y69W-2cfeA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.38A 3abmC-2cfeA:
undetectable
3abmJ-2cfeA:
undetectable		 3abmC-2cfeA:
19.17
3abmJ-2cfeA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.35A 3abmP-2cfeA:
undetectable
3abmW-2cfeA:
undetectable		 3abmP-2cfeA:
19.17
3abmW-2cfeA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.35A 3ag3C-2cfeA:
undetectable
3ag3J-2cfeA:
undetectable		 3ag3C-2cfeA:
19.17
3ag3J-2cfeA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 7 ILE A 112
LEU A  60
PHE A  51
THR A  17
 None
 1.05A 3ag4N-2cfeA:
undetectable
3ag4W-2cfeA:
undetectable		 3ag4N-2cfeA:
16.14
3ag4W-2cfeA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 6 GLN A 109
GLY A  73
HIS A  52
HIS A  50
 None
 1.43A 3ai8B-2cfeA:
undetectable		 3ai8B-2cfeA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 6 THR A 117
SER A  97
LEU A  95
THR A 113
 None
None
GOL  A1163 ( 4.7A)
None
 0.83A 3deuB-2cfeA:
undetectable		 3deuB-2cfeA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		5 / 12 ALA A  47
TYR A  46
GLY A  40
ASP A  64
THR A  66
 None
 1.26A 4mm4A-2cfeA:
undetectable		 4mm4A-2cfeA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 7 GLY A  63
GLN A 109
SER A  49
HIS A  52
 None
 1.16A 4ws0A-2cfeA:
undetectable		 4ws0A-2cfeA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		5 / 12 GLY A 107
ILE A  76
ASN A 100
PHE A  34
LEU A  96
 None
 1.02A 5fa8A-2cfeA:
undetectable		 5fa8A-2cfeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.30A 5xdqC-2cfeA:
undetectable
5xdqJ-2cfeA:
undetectable		 5xdqC-2cfeA:
19.17
5xdqJ-2cfeA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2cfe ALLERGEN
(Malassezia
sympodialis) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.33A 5xdqP-2cfeA:
undetectable
5xdqW-2cfeA:
undetectable		 5xdqP-2cfeA:
19.17
5xdqW-2cfeA:
15.82