SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 8 ILE A 161
LEU A 126
GLU A 186
ALA A 187
VAL A 189
 None
MPD  A1242 (-4.6A)
None
None
None
 1.38A 1a29A-2cffA:
undetectable		 1a29A-2cffA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		3 / 3 ILE A  56
LEU A  52
VAL A  50
 None
 0.46A 1mz9B-2cffA:
undetectable		 1mz9B-2cffA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		4 / 6 ARG A  16
ARG A 224
ILE A 230
TYR A  28
 None
 1.23A 2yfbB-2cffA:
undetectable		 2yfbB-2cffA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.18A 3uboB-2cffA:
2.7		 3uboB-2cffA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		4 / 7 ASP A   8
VAL A 162
ILE A 166
VAL A  50
 None
 0.74A 3ufnB-2cffA:
undetectable		 3ufnB-2cffA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4e3aA-2cffA:
undetectable		 4e3aA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.19A 4e3aB-2cffA:
undetectable		 4e3aB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.06A 4jksA-2cffA:
undetectable		 4jksA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.05A 4jksB-2cffA:
undetectable		 4jksB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4jkuB-2cffA:
undetectable		 4jkuB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.05A 4k8kA-2cffA:
undetectable		 4k8kA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.05A 4k8kB-2cffA:
undetectable		 4k8kB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.17A 4k8pA-2cffA:
undetectable		 4k8pA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4k8pB-2cffA:
undetectable		 4k8pB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.17A 4k8tA-2cffA:
undetectable		 4k8tA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.17A 4k8tB-2cffA:
undetectable		 4k8tB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4k93A-2cffA:
undetectable		 4k93A-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4k93B-2cffA:
undetectable		 4k93B-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4k9cA-2cffA:
undetectable		 4k9cA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.17A 4k9cB-2cffA:
undetectable		 4k9cB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.14A 4k9iA-2cffA:
undetectable		 4k9iA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.14A 4k9iB-2cffA:
undetectable		 4k9iB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4kadA-2cffA:
undetectable		 4kadA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.15A 4kadB-2cffA:
undetectable		 4kadB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.06A 4kanA-2cffA:
undetectable		 4kanA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.06A 4kanB-2cffA:
undetectable		 4kanB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.05A 4lbgA-2cffA:
undetectable		 4lbgA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 12 ILE A 197
GLY A 195
GLY A 196
GLU A 174
THR A 180
 None
 1.05A 4lbgB-2cffA:
undetectable		 4lbgB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.14A 4lbxA-2cffA:
undetectable		 4lbxA-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.15A 4lbxB-2cffA:
undetectable		 4lbxB-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.16A 4lc4A-2cffA:
2.9		 4lc4A-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		6 / 12 ILE A 197
GLY A 195
GLY A 196
LEU A 231
GLU A 174
THR A 180
 None
 1.17A 4lc4B-2cffA:
undetectable		 4lc4B-2cffA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		3 / 4 ARG A  11
GLY A  12
GLU A  61
 None
 0.66A 4z2dB-2cffA:
undetectable
4z2dC-2cffA:
undetectable		 4z2dB-2cffA:
19.48
4z2dC-2cffA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 9 VAL A  36
VAL A  14
LEU A  39
GLY A 223
VAL A  49
 None
 1.11A 6czmA-2cffA:
undetectable
6czmB-2cffA:
undetectable		 6czmA-2cffA:
21.81
6czmB-2cffA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 9 VAL A  36
VAL A  14
LEU A  39
GLY A 223
VAL A  49
 None
 1.10A 6czmB-2cffA:
undetectable
6czmC-2cffA:
undetectable		 6czmB-2cffA:
21.81
6czmC-2cffA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 9 VAL A  36
VAL A  14
LEU A  39
GLY A 223
VAL A  49
 None
 1.11A 6czmD-2cffA:
undetectable
6czmE-2cffA:
undetectable		 6czmD-2cffA:
21.81
6czmE-2cffA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2cff 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)
METHYLIDENEAMINO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE
(Thermotoga
maritima) 		5 / 10 VAL A  36
VAL A  14
LEU A  39
GLY A 223
VAL A  49
 None
 1.11A 6czmE-2cffA:
undetectable
6czmF-2cffA:
undetectable		 6czmE-2cffA:
21.81
6czmF-2cffA:
21.81