SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_D_ADND604_2 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 5	THR A 2 GLU A 30 THR A 72 HIS A 61	None	1.36A	1d4fD-2cj3A: undetectable	1d4fD-2cj3A: 13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.43A	1oe1A-2cj3A: undetectable	1oe1A-2cj3A: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	5 / 5	HIS A 39 CYH A 89 PRO A 91 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 ( 4.9A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.80A	1oe2A-2cj3A: 6.8	1oe2A-2cj3A: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.46A	1oe3A-2cj3A: undetectable	1oe3A-2cj3A: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.36A	2fqdA-2cj3A: 3.2	2fqdA-2cj3A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.32A	2fqeA-2cj3A: undetectable	2fqeA-2cj3A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.32A	2fqfA-2cj3A: undetectable	2fqfA-2cj3A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.30A	2fqgA-2cj3A: undetectable	2fqgA-2cj3A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.43A	2xxgA-2cj3A: 7.6	2xxgA-2cj3A: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	5 / 5	HIS A 39 CYH A 89 PRO A 91 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 ( 4.9A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.84A	2xxgC-2cj3A: 7.4	2xxgC-2cj3A: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_B_RABB602_2 (ADENOSYLHOMOCYSTEINA SE)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 5	THR A 2 GLU A 30 THR A 72 HIS A 61	None	1.37A	3glqB-2cj3A: undetectable	3glqB-2cj3A: 12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	2cj3	PLASTOCYANIN (Nostoc sp. PCC 7120)	4 / 4	HIS A 39 CYH A 89 HIS A 92 MET A 97	CU A 106 (-3.1A) CU A 106 (-2.1A) CU A 106 (-3.1A) CU A 106 (-2.8A)	0.27A	4ef3A-2cj3A: undetectable	4ef3A-2cj3A: 11.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4F_D_ADND604_2","S-ADENOSYLHOMOCYSTEINE HYDROLASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"THR A   2;GLU A  30;THR A  72;HIS A  61","None","1.36A","1d4fD-2cj3A:undetectable","1d4fD-2cj3A:13.87"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.43A","1oe1A-2cj3A:undetectable","1oe1A-2cj3A:17.81"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",5,"HIS A  39;CYH A  89;PRO A  91;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 ( 4.9A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.80A","1oe2A-2cj3A:6.8","1oe2A-2cj3A:17.81"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.46A","1oe3A-2cj3A:undetectable","1oe3A-2cj3A:17.81"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.36A","2fqdA-2cj3A:3.2","2fqdA-2cj3A:11.70"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.32A","2fqeA-2cj3A:undetectable","2fqeA-2cj3A:11.70"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.32A","2fqfA-2cj3A:undetectable","2fqfA-2cj3A:11.70"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.30A","2fqgA-2cj3A:undetectable","2fqgA-2cj3A:11.70"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.43A","2xxgA-2cj3A:7.6","2xxgA-2cj3A:16.56"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",5,"HIS A  39;CYH A  89;PRO A  91;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 ( 4.9A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.84A","2xxgC-2cj3A:7.4","2xxgC-2cj3A:16.56"],["3GLQ_B_RABB602_2","ADENOSYLHOMOCYSTEINASE","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"THR A   2;GLU A  30;THR A  72;HIS A  61","None","1.37A","3glqB-2cj3A:undetectable","3glqB-2cj3A:12.05"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","2cj3","PLASTOCYANIN","Nostoc sp. PCC 7120",4,"HIS A  39;CYH A  89;HIS A  92;MET A  97"," CU A 106 (-3.1A); CU A 106 (-2.1A); CU A 106 (-3.1A); CU A 106 (-2.8A)","0.27A","4ef3A-2cj3A:undetectable","4ef3A-2cj3A:11.86"]]