SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		3 / 3 ASN A 113
ALA A  97
ASN A 129
 None
 0.78A 1n4fA-2cjlA:
4.5		 1n4fA-2cjlA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		4 / 6 TRP A 147
TYR A  42
GLY A 154
SER A 176
 None
 1.11A 2a3cA-2cjlA:
undetectable		 2a3cA-2cjlA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		4 / 6 TRP A 147
TYR A  42
GLY A 154
SER A 176
 None
 1.11A 2a3cB-2cjlA:
undetectable		 2a3cB-2cjlA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		4 / 8 THR A 159
GLN A 152
ASP A 162
TYR A  42
 None
 1.41A 2xz5A-2cjlA:
undetectable
2xz5C-2cjlA:
undetectable		 2xz5A-2cjlA:
21.78
2xz5C-2cjlA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		4 / 5 GLY A 210
GLY A 211
ASN A 212
GLU A 208
 None
 1.12A 4fglC-2cjlA:
undetectable		 4fglC-2cjlA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		3 / 3 GLN A 152
THR A 153
THR A 159
 None
 0.77A 4fu9A-2cjlA:
undetectable		 4fu9A-2cjlA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		3 / 3 GLN A 152
THR A 153
THR A 159
 None
 0.75A 4fufA-2cjlA:
undetectable		 4fufA-2cjlA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		4 / 5 THR A 144
GLY A 106
VAL A  75
TYR A 116
 None
 1.16A 4grkA-2cjlA:
undetectable		 4grkA-2cjlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2cjl SECRETED CHITINASE
(Streptomyces
coelicolor) 		4 / 6 GLY A 145
TYR A 148
LEU A 123
VAL A 134
 None
 0.77A 5x80A-2cjlA:
undetectable
5x80B-2cjlA:
undetectable		 5x80A-2cjlA:
21.89
5x80B-2cjlA:
21.89