SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A130_2 (FATTY ACID-BINDING PROTEIN, LIVER)	2cjt	UNC-13 HOMOLOG A (Rattus norvegicus)	4 / 7	PHE A 49 LEU A 26 LEU A 60 GLU A 46	FMT A1139 ( 4.3A) None None None	1.05A	2jn3A-2cjtA: undetectable	2jn3A-2cjtA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_C_ACTC502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2cjt	UNC-13 HOMOLOG A (Rattus norvegicus)	3 / 3	PRO A 93 ASP A 124 GLU A 95	EDO A1132 (-3.9A) EDO A1132 ( 3.4A) EDO A1133 ( 4.5A)	0.67A	3v4tC-2cjtA: undetectable	3v4tC-2cjtA: 16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE506_1 (HEMOLYTIC LECTIN CEL-III)	2cjt	UNC-13 HOMOLOG A (Rattus norvegicus)	4 / 6	THR A 22 ASN A 66 GLY A 68 ASP A 72	None FMT A1138 (-3.8A) FMT A1137 ( 3.1A) EDO A1134 (-2.9A)	1.18A	3w9tE-2cjtA: undetectable	3w9tE-2cjtA: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B53_B_ACTB1445_0 (IG GAMMA-4 CHAIN C REGION)	2cjt	UNC-13 HOMOLOG A (Rattus norvegicus)	3 / 3	GLU A 90 GLY A 92 SER A 88	None EDO A1132 (-3.5A) None	0.68A	4b53B-2cjtA: 2.9	4b53B-2cjtA: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MRA_B_DM2B204_1 (SORCIN)	2cjt	UNC-13 HOMOLOG A (Rattus norvegicus)	4 / 6	PHE A 20 THR A 22 ASP A 72 GLY A 68	None None EDO A1134 (-2.9A) FMT A1137 ( 3.1A)	1.03A	5mraA-2cjtA: undetectable 5mraB-2cjtA: undetectable	5mraA-2cjtA: 23.16 5mraB-2cjtA: 23.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2JN3_A_JN3A130_2","FATTY ACID-BINDING PROTEIN, LIVER","2cjt","UNC-13 HOMOLOG A","Rattus norvegicus",4,"PHE A  49;LEU A  26;LEU A  60;GLU A  46","FMT A1139 ( 4.3A);None;None;None","1.05A","2jn3A-2cjtA:undetectable","2jn3A-2cjtA:24.06"],["3V4T_C_ACTC502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2cjt","UNC-13 HOMOLOG A","Rattus norvegicus",3,"PRO A  93;ASP A 124;GLU A  95","EDO A1132 (-3.9A);EDO A1132 ( 3.4A);EDO A1133 ( 4.5A)","0.67A","3v4tC-2cjtA:undetectable","3v4tC-2cjtA:16.71"],["3W9T_E_W9TE506_1","HEMOLYTIC LECTIN CEL-III","2cjt","UNC-13 HOMOLOG A","Rattus norvegicus",4,"THR A  22;ASN A  66;GLY A  68;ASP A  72","None;FMT A1138 (-3.8A);FMT A1137 ( 3.1A);EDO A1134 (-2.9A)","1.18A","3w9tE-2cjtA:undetectable","3w9tE-2cjtA:14.86"],["4B53_B_ACTB1445_0","IG GAMMA-4 CHAIN C REGION","2cjt","UNC-13 HOMOLOG A","Rattus norvegicus",3,"GLU A  90;GLY A  92;SER A  88","None;EDO A1132 (-3.5A);None","0.68A","4b53B-2cjtA:2.9","4b53B-2cjtA:22.54"],["5MRA_B_DM2B204_1","SORCIN;SORCIN","2cjt","UNC-13 HOMOLOG A","Rattus norvegicus",4,"PHE A  20;THR A  22;ASP A  72;GLY A  68","None;None;EDO A1134 (-2.9A);FMT A1137 ( 3.1A)","1.03A","5mraA-2cjtA:undetectable;5mraB-2cjtA:undetectable","5mraA-2cjtA:23.16;5mraB-2cjtA:23.16"]]