SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ckn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 2ckn BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1
(Mus
musculus) 		3 / 3 PRO A  82
ASP A  84
ASP A  79
 None
 0.66A 1sqfA-2cknA:
undetectable		 1sqfA-2cknA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2ckn BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1
(Mus
musculus) 		4 / 5 ASP A  79
SER A  80
VAL A  34
GLY A  37
 None
 1.03A 3rxhA-2cknA:
undetectable		 3rxhA-2cknA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2ckn BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1
(Mus
musculus) 		5 / 10 ALA A  83
LEU A  40
ASP A  84
VAL A  77
TRP A  55
 None
 1.49A 6g2pB-2cknA:
undetectable		 6g2pB-2cknA:
13.17