SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.85A 1a7yB-2cl2A:
undetectable		 1a7yB-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.95A 1c6yA-2cl2A:
undetectable		 1c6yA-2cl2A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.92A 1dscC-2cl2A:
undetectable		 1dscC-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.76A 1fjaC-2cl2A:
undetectable		 1fjaC-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.76A 1fjaD-2cl2A:
undetectable		 1fjaD-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 ILE A 119
ASP A 124
GLY A 176
PHE A 179
ASN A 180
 None
 1.20A 1i00B-2cl2A:
undetectable		 1i00B-2cl2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.88A 1i3wE-2cl2A:
undetectable		 1i3wE-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.88A 1i3wG-2cl2A:
undetectable		 1i3wG-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.86A 1i3wG-2cl2A:
undetectable		 1i3wG-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.86A 1i3wH-2cl2A:
undetectable		 1i3wH-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 6 HIS A 241
ASP A 156
ASP A 160
PRO A 111
 None
 1.31A 1ilqA-2cl2A:
0.0
1ilqC-2cl2A:
undetectable		 1ilqA-2cl2A:
11.70
1ilqC-2cl2A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.85A 1ohrB-2cl2A:
undetectable		 1ohrB-2cl2A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.86A 1unjL-2cl2A:
undetectable		 1unjL-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.86A 1unjL-2cl2A:
undetectable		 1unjL-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.86A 1unjX-2cl2A:
undetectable		 1unjX-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.87A 1unmE-2cl2A:
undetectable		 1unmE-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.83A 1unmE-2cl2A:
undetectable		 1unmE-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.83A 1unmF-2cl2A:
undetectable		 1unmF-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.80A 1unmF-2cl2A:
undetectable		 1unmF-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.81A 209dC-2cl2A:
undetectable		 209dC-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
THR A 252
PRO A 100
 None
 0.67A 209dC-2cl2A:
undetectable		 209dC-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 8 HIS A  20
VAL A  34
LEU A  44
THR A  45
 None
 0.78A 2gehA-2cl2A:
undetectable		 2gehA-2cl2A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 7 LEU A  54
ILE A 248
ARG A  75
SER A  76
 None
 1.06A 2hc4A-2cl2A:
undetectable		 2hc4A-2cl2A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 1.01A 2idwA-2cl2A:
undetectable		 2idwA-2cl2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 252
PRO A 100
THR A  98
 None
 0.87A 316dC-2cl2A:
undetectable		 316dC-2cl2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 PRO A 100
LEU A 251
ARG A  55
 None
None
NAG  A1299 (-3.0A)
 0.87A 3aqiA-2cl2A:
undetectable		 3aqiA-2cl2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 5 ASN A 158
ALA A 139
GLY A 164
THR A 105
 None
 0.83A 3dl9A-2cl2A:
undetectable		 3dl9A-2cl2A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 1.00A 3ekqB-2cl2A:
undetectable		 3ekqB-2cl2A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 1.04A 3el0B-2cl2A:
undetectable		 3el0B-2cl2A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 PRO A  93
PHE A 253
ALA A  56
 None
 0.69A 3itaD-2cl2A:
undetectable		 3itaD-2cl2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.91A 3pwrB-2cl2A:
undetectable		 3pwrB-2cl2A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 8 ALA A 129
THR A 131
GLN A 168
THR A 151
 None
 0.83A 3rglA-2cl2A:
undetectable		 3rglA-2cl2A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 ASN A 153
ALA A 150
ARG A 144
 None
 0.81A 3tj7C-2cl2A:
1.3
3tj7D-2cl2A:
1.3		 3tj7C-2cl2A:
20.46
3tj7D-2cl2A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 5 LEU A  52
GLY A  11
PHE A  18
ASN A   8
 None
 1.14A 3uq6B-2cl2A:
undetectable		 3uq6B-2cl2A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 ILE A 119
ASP A 124
GLY A 176
PHE A 179
ASN A 180
 None
 1.24A 4eb4C-2cl2A:
undetectable		 4eb4C-2cl2A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 119
ASP A 124
GLY A 176
PHE A 179
ASN A 180
 None
 1.26A 4eb4D-2cl2A:
undetectable		 4eb4D-2cl2A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 GLN A 298
THR A  82
THR A  81
 None
 0.71A 4fu9A-2cl2A:
undetectable		 4fu9A-2cl2A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 GLN A 298
THR A  82
THR A  81
 None
 0.72A 4fufA-2cl2A:
undetectable		 4fufA-2cl2A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.89A 4jecB-2cl2A:
undetectable		 4jecB-2cl2A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.89A 4njtA-2cl2A:
undetectable		 4njtA-2cl2A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.93A 4njtC-2cl2A:
undetectable		 4njtC-2cl2A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 6 GLU A 107
ASP A 109
ASP A 243
ARG A 191
 None
 1.34A 4ntxA-2cl2A:
undetectable
4ntxC-2cl2A:
undetectable		 4ntxA-2cl2A:
21.62
4ntxC-2cl2A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.82A 4rvjA-2cl2A:
undetectable		 4rvjA-2cl2A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.82A 4rvjC-2cl2A:
undetectable		 4rvjC-2cl2A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A  29
ASP A  25
PRO A  26
GLU A 107
TRP A  99
 None
 1.16A 5bw4A-2cl2A:
undetectable		 5bw4A-2cl2A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 ARG A  73
THR A  27
ASP A  25
 None
 0.93A 5g5gA-2cl2A:
undetectable
5g5gB-2cl2A:
undetectable		 5g5gA-2cl2A:
20.88
5g5gB-2cl2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A  74
HIS A  20
ASN A 250
PHE A  87
ALA A 102
 None
 1.06A 5igyA-2cl2A:
0.5		 5igyA-2cl2A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A  74
HIS A  20
ASN A 250
PHE A  87
ALA A 102
 None
 1.04A 5ih0A-2cl2A:
0.6		 5ih0A-2cl2A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 1.07A 5kqxB-2cl2A:
undetectable		 5kqxB-2cl2A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.97A 5kqyA-2cl2A:
undetectable		 5kqyA-2cl2A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 ASN A 207
ALA A 205
GLY A 185
THR A 171
PRO A 170
 None
 1.23A 5kr2C-2cl2A:
undetectable		 5kr2C-2cl2A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 11 ILE A 291
ILE A 249
VAL A  89
ASN A 128
ILE A 119
 None
 1.10A 5lg3A-2cl2A:
undetectable		 5lg3A-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 ILE A 249
PHE A  87
ASN A 128
ASP A 117
ILE A 119
 None
 1.47A 5lg3D-2cl2A:
undetectable		 5lg3D-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 291
ILE A 249
VAL A  89
ASN A 128
ILE A 119
 None
 1.09A 5lg3F-2cl2A:
undetectable		 5lg3F-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 291
ILE A 249
VAL A  89
TRP A 103
ILE A 119
 None
 1.16A 5lg3F-2cl2A:
undetectable		 5lg3F-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 291
ILE A 249
VAL A  89
ASN A 128
ILE A 119
 None
 1.08A 5lg3G-2cl2A:
undetectable		 5lg3G-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 291
ILE A 249
VAL A  89
TRP A 103
ILE A 119
 None
 1.14A 5lg3G-2cl2A:
undetectable		 5lg3G-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 291
ILE A 249
VAL A  89
ASN A 128
ILE A 119
 None
 1.10A 5lg3H-2cl2A:
undetectable		 5lg3H-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 291
ILE A 249
VAL A  89
TRP A 103
ILE A 119
 None
 1.15A 5lg3H-2cl2A:
undetectable		 5lg3H-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A 291
ILE A 249
VAL A  89
ASN A 128
ILE A 119
 None
 1.03A 5lg3J-2cl2A:
undetectable		 5lg3J-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A 291
ILE A 249
VAL A  89
TRP A 103
ILE A 119
 None
 1.15A 5lg3J-2cl2A:
undetectable		 5lg3J-2cl2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 119
ILE A 118
ILE A 247
ILE A 249
ILE A 248
 None
 1.04A 5murE-2cl2A:
undetectable		 5murE-2cl2A:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 PRO A 100
ILE A 119
ILE A 249
ILE A 248
ILE A 247
 None
 0.87A 5murE-2cl2A:
undetectable		 5murE-2cl2A:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 7 ASP A 243
GLY A 114
ASP A 106
ASN A 112
 None
 0.96A 5nnwD-2cl2A:
undetectable		 5nnwD-2cl2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		4 / 7 ASP A 243
GLY A 114
ASP A 106
ASN A 112
 None
 1.00A 5no9D-2cl2A:
undetectable		 5no9D-2cl2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 9 ILE A 119
ASP A 124
GLY A 176
PHE A 179
ASN A 180
 None
 1.29A 5x66C-2cl2A:
undetectable		 5x66C-2cl2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 119
ASP A 124
GLY A 176
PHE A 179
ASN A 180
 None
 1.30A 5x66D-2cl2A:
undetectable		 5x66D-2cl2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		3 / 3 VAL A 296
TYR A 297
GLU A 104
 None
 0.93A 5zmqD-2cl2A:
undetectable
5zmqE-2cl2A:
undetectable		 5zmqD-2cl2A:
20.86
5zmqE-2cl2A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 2cl2 PUTATIVE
LAMINARINASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A  52
VAL A  89
ILE A 119
ILE A 248
ILE A 291
 None
 0.94A 6dh3B-2cl2A:
undetectable		 6dh3B-2cl2A:
14.29