SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cl8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2cl8 DECTIN-1
(Mus
musculus) 		3 / 3 SER A 129
TYR A 131
ASP A 158
 CA  A1245 ( 4.8A)
None
CA  A1245 (-3.3A)
 0.81A 4rp8C-2cl8A:
undetectable		 4rp8C-2cl8A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2cl8 DECTIN-1
(Mus
musculus) 		5 / 12 GLU A 162
ILE A 157
LEU A 182
GLY A 181
ALA A 198
 CA  A1245 (-2.2A)
None
None
None
None
 1.22A 5x5qB-2cl8A:
undetectable		 5x5qB-2cl8A:
18.07