SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 2cly ATP SYNTHASE D
CHAIN, MITOCHONDRIAL
(Bos
taurus) 		3 / 3 GLU B  35
ASN B  34
TRP B  12
 None
 1.18A 1r15C-2clyB:
undetectable		 1r15C-2clyB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 2cly ATP SYNTHASE D
CHAIN, MITOCHONDRIAL
(Bos
taurus) 		3 / 3 GLU B  35
ASN B  34
TRP B  12
 None
 1.14A 1r15D-2clyB:
undetectable		 1r15D-2clyB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 2cly ATP SYNTHASE D
CHAIN, MITOCHONDRIAL
(Bos
taurus) 		3 / 3 GLU B  35
ASN B  34
TRP B  12
 None
 1.18A 1r15E-2clyB:
undetectable		 1r15E-2clyB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 2cly ATP SYNTHASE D
CHAIN, MITOCHONDRIAL
(Bos
taurus) 		3 / 3 GLU B  35
ASN B  34
TRP B  12
 None
 1.20A 1r15F-2clyB:
undetectable		 1r15F-2clyB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 2cly ATP SYNTHASE B
CHAIN, MITOCHONDRIAL
ATP SYNTHASE D
CHAIN, MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 6 GLN B  23
ARG A 121
GLU B  35
LEU A 124
 None
 1.19A 4ax8A-2clyB:
undetectable		 4ax8A-2clyB:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2cly ATP SYNTHASE B
CHAIN, MITOCHONDRIAL
(Bos
taurus) 		3 / 3 PHE A 125
ARG A 129
GLN A 128
 None
 0.74A 6g1pB-2clyA:
undetectable		 6g1pB-2clyA:
20.95