SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cm6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T86_A_CAMA1422_0 (CYTOCHROME P450-CAM)	2cm6	RABPHILIN-3A (Rattus norvegicus)	4 / 8	THR A 602 THR A 596 VAL A 629 VAL A 580	None	0.80A	1t86A-2cm6A: undetectable	1t86A-2cm6A: 15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NAI_C_URFC521_1 (RNA DEPENDENT RNA POLYMERASE)	2cm6	RABPHILIN-3A (Rattus norvegicus)	4 / 5	ASP A 571 ASP A 631 ASP A 639 ARG A 534	CA A1679 ( 2.2A) CA A1679 ( 2.6A) CA A1680 (-3.1A) None	1.34A	3naiC-2cm6A: undetectable	3naiC-2cm6A: 14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MDB_A_RLTA401_1 (MARINER MOS1 TRANSPOSASE)	2cm6	RABPHILIN-3A (Rattus norvegicus)	4 / 6	ASP A 633 ASP A 571 ASN A 573 ASP A 639	CA A1680 ( 2.1A) CA A1679 ( 2.2A) None CA A1680 (-3.1A)	1.15A	4mdbA-2cm6A: undetectable	4mdbA-2cm6A: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXD_C_RBVC502_2 (ADENOSYLHOMOCYSTEINA SE)	2cm6	RABPHILIN-3A (Rattus norvegicus)	3 / 3	THR A 602 HIS A 673 LEU A 675	None	0.88A	5axdC-2cm6A: undetectable	5axdC-2cm6A: 15.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1T86_A_CAMA1422_0","CYTOCHROME P450-CAM","2cm6","RABPHILIN-3A","Rattus norvegicus",4,"THR A 602;THR A 596;VAL A 629;VAL A 580","None","0.80A","1t86A-2cm6A:undetectable","1t86A-2cm6A:15.97"],["3NAI_C_URFC521_1","RNA DEPENDENT RNA POLYMERASE","2cm6","RABPHILIN-3A","Rattus norvegicus",4,"ASP A 571;ASP A 631;ASP A 639;ARG A 534"," CA A1679 ( 2.2A); CA A1679 ( 2.6A); CA A1680 (-3.1A);None","1.34A","3naiC-2cm6A:undetectable","3naiC-2cm6A:14.51"],["4MDB_A_RLTA401_1","MARINER MOS1 TRANSPOSASE","2cm6","RABPHILIN-3A","Rattus norvegicus",4,"ASP A 633;ASP A 571;ASN A 573;ASP A 639"," CA A1680 ( 2.1A); CA A1679 ( 2.2A);None; CA A1680 (-3.1A)","1.15A","4mdbA-2cm6A:undetectable","4mdbA-2cm6A:23.95"],["5AXD_C_RBVC502_2","ADENOSYLHOMOCYSTEINASE","2cm6","RABPHILIN-3A","Rattus norvegicus",3,"THR A 602;HIS A 673;LEU A 675","None","0.88A","5axdC-2cm6A:undetectable","5axdC-2cm6A:15.51"]]