SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JGL_L_ESTL911_1 (IG GAMMA-1-CHAIN IG KAPPA-CHAIN)	2cnm	MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18 (Salmonella enterica)	5 / 10	GLY A 37 ALA A 15 LEU A 7 PHE A 32 TRP A 27	None	1.32A	1jglH-2cnmA: undetectable 1jglL-2cnmA: undetectable	1jglH-2cnmA: 16.97 1jglL-2cnmA: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFJ_A_SAMA501_0 (MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1)	2cnm	MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18 (Salmonella enterica)	5 / 12	LEU A 66 THR A 65 ALA A 64 ILE A 56 LEU A 41	None	0.88A	5nfjA-2cnmA: undetectable	5nfjA-2cnmA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_C_GLYC713_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	2cnm	MODIFICATION OF 30S RIBOSOMAL SUBUNIT PROTEIN S18 (Salmonella enterica)	3 / 3	GLN A 36 TYR A 40 ASN A 42	None	1.01A	6dwdC-2cnmA: undetectable	6dwdC-2cnmA: 12.14