SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2co7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 2co7 SAFA PILUS SUBUNIT
(Salmonella
enterica) 		5 / 10 GLU A  56
PHE A  57
PHE A 111
THR A  70
LEU A  89
 None
 1.09A 2w3aB-2co7A:
undetectable		 2w3aB-2co7A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2co7 SAFA PILUS SUBUNIT
(Salmonella
enterica) 		5 / 10 THR A 122
ILE A 119
LEU A 117
VAL A  59
GLY A  61
 None
 1.16A 2wd9C-2co7A:
undetectable		 2wd9C-2co7A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2co7 SAFA PILUS SUBUNIT
(Salmonella
enterica) 		3 / 3 SER A  91
THR A  72
PHE A  57
 None
 0.74A 2x91A-2co7A:
undetectable		 2x91A-2co7A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2co7 SAFA PILUS SUBUNIT
(Salmonella
enterica) 		4 / 8 SER A  51
ASN A  50
GLY A 141
GLN A 143
 None
 0.89A 4af0A-2co7A:
undetectable		 4af0A-2co7A:
12.48