SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 2cop ACYL-COENZYME A
BINDING DOMAIN
CONTAINING 6
(Homo
sapiens) 		3 / 3 VAL A  43
VAL A  41
TRP A  65
 None
 0.87A 1av2C-2copA:
undetectable
1av2D-2copA:
undetectable		 1av2C-2copA:
13.43
1av2D-2copA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 2cop ACYL-COENZYME A
BINDING DOMAIN
CONTAINING 6
(Homo
sapiens) 		3 / 3 VAL A  43
VAL A  41
TRP A  65
 None
 0.85A 1w5uC-2copA:
undetectable
1w5uD-2copA:
undetectable		 1w5uC-2copA:
13.43
1w5uD-2copA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 2cop ACYL-COENZYME A
BINDING DOMAIN
CONTAINING 6
(Homo
sapiens) 		3 / 3 VAL A  41
TRP A  65
VAL A  43
 None
 0.79A 2izqA-2copA:
undetectable
2izqB-2copA:
undetectable		 2izqA-2copA:
13.43
2izqB-2copA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 2cop ACYL-COENZYME A
BINDING DOMAIN
CONTAINING 6
(Homo
sapiens) 		3 / 3 VAL A  43
VAL A  41
TRP A  65
 None
 0.68A 3l8lA-2copA:
undetectable
3l8lB-2copA:
undetectable		 3l8lA-2copA:
13.43
3l8lB-2copA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 2cop ACYL-COENZYME A
BINDING DOMAIN
CONTAINING 6
(Homo
sapiens) 		3 / 3 VAL A  43
VAL A  41
TRP A  65
 None
 0.80A 3l8lC-2copA:
undetectable
3l8lD-2copA:
undetectable		 3l8lC-2copA:
13.43
3l8lD-2copA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 2cop ACYL-COENZYME A
BINDING DOMAIN
CONTAINING 6
(Homo
sapiens) 		3 / 3 ASP A  88
HIS A  18
LYS A  85
 None
 1.01A 4qzuD-2copA:
undetectable		 4qzuD-2copA:
26.32