SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 2cov BETA-1,3-XYLANASE
(Alcaligenes
sp.
XY-234) 		3 / 3 ASN D 469
ALA D 427
ARG D 429
 None
 0.83A 3tj7C-2covD:
undetectable
3tj7D-2covD:
undetectable		 3tj7C-2covD:
17.09
3tj7D-2covD:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 2cov BETA-1,3-XYLANASE
(Alcaligenes
sp.
XY-234) 		4 / 4 ASN D 389
LEU D 436
PHE D 432
TYR D 440
 None
 1.47A 4u14A-2covD:
undetectable		 4u14A-2covD:
11.28