SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DF7_A_MTXA501_2 (DIHYDROFOLATE REDUCTASE)	2cow	KINESIN-LIKE PROTEIN KIF13B (Homo sapiens)	3 / 3	TRP A 53 ARG A 25 THR A 52	None	1.00A	1df7A-2cowA: undetectable	1df7A-2cowA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CSJ_B_CBLB211_0 (GLUTATHIONE S-TRANSFERASE P)	2cow	KINESIN-LIKE PROTEIN KIF13B (Homo sapiens)	5 / 9	PRO A 87 VAL A 54 GLY A 55 ARG A 41 GLY A 44	None	1.46A	3csjB-2cowA: undetectable	3csjB-2cowA: 23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_J_ACHJ323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	2cow	KINESIN-LIKE PROTEIN KIF13B (Homo sapiens)	4 / 8	LEU A 84 PHE A 48 PHE A 75 TYR A 42	None	1.10A	3rqwF-2cowA: undetectable 3rqwJ-2cowA: undetectable	3rqwF-2cowA: 15.52 3rqwJ-2cowA: 15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYS_A_ACTA402_0 (MCCC FAMILY PROTEIN)	2cow	KINESIN-LIKE PROTEIN KIF13B (Homo sapiens)	4 / 6	SER A 12 ASP A 13 SER A 14 GLU A 16	None	1.22A	4eysA-2cowA: undetectable	4eysA-2cowA: 13.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DF7_A_MTXA501_2","DIHYDROFOLATE REDUCTASE","2cow","KINESIN-LIKE PROTEIN KIF13B","Homo sapiens",3,"TRP A  53;ARG A  25;THR A  52","None","1.00A","1df7A-2cowA:undetectable","1df7A-2cowA:22.64"],["3CSJ_B_CBLB211_0","GLUTATHIONE S-TRANSFERASE P","2cow","KINESIN-LIKE PROTEIN KIF13B","Homo sapiens",5,"PRO A  87;VAL A  54;GLY A  55;ARG A  41;GLY A  44","None","1.46A","3csjB-2cowA:undetectable","3csjB-2cowA:23.00"],["3RQW_J_ACHJ323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","2cow","KINESIN-LIKE PROTEIN KIF13B","Homo sapiens",4,"LEU A  84;PHE A  48;PHE A  75;TYR A  42","None","1.10A","3rqwF-2cowA:undetectable;3rqwJ-2cowA:undetectable","3rqwF-2cowA:15.52;3rqwJ-2cowA:15.52"],["4EYS_A_ACTA402_0","MCCC FAMILY PROTEIN","2cow","KINESIN-LIKE PROTEIN KIF13B","Homo sapiens",4,"SER A  12;ASP A  13;SER A  14;GLU A  16","None","1.22A","4eysA-2cowA:undetectable","4eysA-2cowA:13.54"]]