SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_A_NIOA221_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2cp3	CLIP-115 (Homo sapiens)	4 / 6	THR A 30 PHE A 68 PHE A 59 GLY A 39	None	1.13A	1icuA-2cp3A: undetectable 1icuB-2cp3A: undetectable	1icuA-2cp3A: 17.06 1icuB-2cp3A: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_D_NIOD223_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2cp3	CLIP-115 (Homo sapiens)	4 / 5	PHE A 59 GLY A 39 THR A 30 PHE A 68	None	1.09A	1icuC-2cp3A: undetectable 1icuD-2cp3A: undetectable	1icuC-2cp3A: 17.06 1icuD-2cp3A: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_C_BEZC522_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2cp3	CLIP-115 (Homo sapiens)	4 / 6	THR A 30 PHE A 68 PHE A 59 GLY A 39	None	1.08A	1kqbC-2cp3A: undetectable 1kqbD-2cp3A: undetectable	1kqbC-2cp3A: 17.84 1kqbD-2cp3A: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_D_BEZD523_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2cp3	CLIP-115 (Homo sapiens)	4 / 6	PHE A 59 GLY A 39 THR A 30 PHE A 68	None	1.06A	1kqbC-2cp3A: undetectable 1kqbD-2cp3A: undetectable	1kqbC-2cp3A: 17.84 1kqbD-2cp3A: 17.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICU_A_NIOA221_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2cp3","CLIP-115","Homo sapiens",4,"THR A  30;PHE A  68;PHE A  59;GLY A  39","None","1.13A","1icuA-2cp3A:undetectable;1icuB-2cp3A:undetectable","1icuA-2cp3A:17.06;1icuB-2cp3A:17.06"],["1ICU_D_NIOD223_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2cp3","CLIP-115","Homo sapiens",4,"PHE A  59;GLY A  39;THR A  30;PHE A  68","None","1.09A","1icuC-2cp3A:undetectable;1icuD-2cp3A:undetectable","1icuC-2cp3A:17.06;1icuD-2cp3A:17.06"],["1KQB_C_BEZC522_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2cp3","CLIP-115","Homo sapiens",4,"THR A  30;PHE A  68;PHE A  59;GLY A  39","None","1.08A","1kqbC-2cp3A:undetectable;1kqbD-2cp3A:undetectable","1kqbC-2cp3A:17.84;1kqbD-2cp3A:17.84"],["1KQB_D_BEZD523_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2cp3","CLIP-115","Homo sapiens",4,"PHE A  59;GLY A  39;THR A  30;PHE A  68","None","1.06A","1kqbC-2cp3A:undetectable;1kqbD-2cp3A:undetectable","1kqbC-2cp3A:17.84;1kqbD-2cp3A:17.84"]]