SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cph'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 5 GLU A 538
THR A 528
LEU A 535
LEU A 524
 None
 1.12A 1u18B-2cphA:
undetectable		 1u18B-2cphA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 8 LEU A 530
VAL A 491
LEU A 493
VAL A 509
 None
 0.83A 2zujA-2cphA:
undetectable		 2zujA-2cphA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 7 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 1.04A 2zxwN-2cphA:
undetectable
2zxwW-2cphA:
undetectable		 2zxwN-2cphA:
12.76
2zxwW-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 8 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 0.91A 3abkA-2cphA:
undetectable
3abkJ-2cphA:
undetectable		 3abkA-2cphA:
12.76
3abkJ-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 7 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 0.96A 3ag2N-2cphA:
undetectable
3ag2W-2cphA:
undetectable		 3ag2N-2cphA:
12.76
3ag2W-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 7 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 1.06A 3ag4N-2cphA:
undetectable
3ag4W-2cphA:
undetectable		 3ag4N-2cphA:
12.76
3ag4W-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 6 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 0.90A 5b1aN-2cphA:
undetectable
5b1aW-2cphA:
undetectable		 5b1aN-2cphA:
12.76
5b1aW-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 8 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 0.90A 5zcoA-2cphA:
undetectable
5zcoJ-2cphA:
undetectable		 5zcoA-2cphA:
12.76
5zcoJ-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		4 / 8 ILE A 478
LEU A 481
PHE A 482
ARG A 467
 None
 0.86A 5zcqN-2cphA:
undetectable
5zcqW-2cphA:
undetectable		 5zcqN-2cphA:
12.76
5zcqW-2cphA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2cph RNA BINDING MOTIF
PROTEIN 19
(Mus
musculus) 		3 / 3 LEU A 481
SER A 483
PHE A 482
 None
 0.67A 6fgcA-2cphA:
undetectable		 6fgcA-2cphA:
12.65