SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 2cpr EXOSOME COMPONENT 10
(Homo
sapiens) 		3 / 3 MET A 569
CYH A 554
PRO A 559
 None
 1.15A 3h52C-2cprA:
undetectable		 3h52C-2cprA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2cpr EXOSOME COMPONENT 10
(Homo
sapiens) 		3 / 3 PRO A 580
LEU A 581
GLN A 505
 None
 0.58A 3hznG-2cprA:
undetectable
3hznH-2cprA:
undetectable		 3hznG-2cprA:
18.35
3hznH-2cprA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 2cpr EXOSOME COMPONENT 10
(Homo
sapiens) 		3 / 3 LYS A 476
ILE A 485
PHE A 486
 None
 1.00A 3j7zS-2cprA:
undetectable
3j7za-2cprA:
undetectable		 3j7zS-2cprA:
20.15
3j7za-2cprA:
7.69