SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cpt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2cpt VACUOLAR SORTING
PROTEIN 4B
(Homo
sapiens) 		4 / 7 ASN A  33
GLU A  35
TYR A  41
GLU A  28
 None
 1.26A 4mj8C-2cptA:
undetectable		 4mj8C-2cptA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2cpt VACUOLAR SORTING
PROTEIN 4B
(Homo
sapiens) 		4 / 7 ASN A  33
GLU A  35
TYR A  41
GLU A  28
 None
 1.23A 4r87I-2cptA:
undetectable		 4r87I-2cptA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 2cpt VACUOLAR SORTING
PROTEIN 4B
(Homo
sapiens) 		3 / 3 ASN A 107
ASP A 110
GLY A 111
 None
 0.44A 5fctB-2cptA:
undetectable		 5fctB-2cptA:
15.23