SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 2cq0 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT 4
(Homo
sapiens) 		5 / 12 ASP A 273
ALA A 283
TYR A 269
SER A 279
GLY A 281
 None
 1.15A 4mmdB-2cq0A:
undetectable		 4mmdB-2cq0A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2cq0 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT 4
(Homo
sapiens) 		5 / 12 LEU A 258
ALA A 296
PHE A 259
ILE A 241
VAL A 243
 None
 0.93A 4nkxB-2cq0A:
undetectable		 4nkxB-2cq0A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2cq0 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT 4
(Homo
sapiens) 		4 / 7 ILE A 285
LEU A 258
ALA A 296
ILE A 241
 None
 0.79A 4y03A-2cq0A:
undetectable		 4y03A-2cq0A:
19.85