SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2cq2 HYPOTHETICAL PROTEIN
LOC91801
(Homo
sapiens) 		5 / 8 LEU A 117
VAL A  64
LEU A  61
VAL A 105
LEU A 115
 None
 1.33A 3kp6A-2cq2A:
undetectable
3kp6B-2cq2A:
undetectable		 3kp6A-2cq2A:
21.79
3kp6B-2cq2A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 2cq2 HYPOTHETICAL PROTEIN
LOC91801
(Homo
sapiens) 		4 / 6 LEU A 117
ALA A  85
SER A  83
VAL A  71
 None
 1.23A 5a6iA-2cq2A:
undetectable		 5a6iA-2cq2A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2cq2 HYPOTHETICAL PROTEIN
LOC91801
(Homo
sapiens) 		5 / 12 TYR A  87
ALA A  73
PHE A  84
SER A  83
CYH A  68
 None
 1.39A 5cprB-2cq2A:
undetectable		 5cprB-2cq2A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2cq2 HYPOTHETICAL PROTEIN
LOC91801
(Homo
sapiens) 		4 / 4 LEU A  61
LEU A  65
SER A  83
ALA A  85
 None
 1.11A 5uunA-2cq2A:
undetectable		 5uunA-2cq2A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2cq2 HYPOTHETICAL PROTEIN
LOC91801
(Homo
sapiens) 		3 / 3 GLY A 102
THR A 114
GLU A 104
 None
 0.66A 6b58A-2cq2A:
undetectable		 6b58A-2cq2A:
13.65