SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2cq4 RNA BINDING MOTIF
PROTEIN 23
(Homo
sapiens) 		4 / 6 ASN A 186
GLU A 228
TYR A 195
PHE A 153
 None
 1.19A 4twdB-2cq4A:
undetectable
4twdC-2cq4A:
undetectable		 4twdB-2cq4A:
16.56
4twdC-2cq4A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2cq4 RNA BINDING MOTIF
PROTEIN 23
(Homo
sapiens) 		4 / 6 ASN A 186
GLU A 228
TYR A 195
PHE A 153
 None
 1.20A 4twdD-2cq4A:
undetectable
4twdE-2cq4A:
undetectable		 4twdD-2cq4A:
16.56
4twdE-2cq4A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2cq4 RNA BINDING MOTIF
PROTEIN 23
(Homo
sapiens) 		5 / 12 LEU A 210
ILE A 181
GLY A 192
ILE A 193
GLY A 212
 None
 0.99A 5d4uC-2cq4A:
undetectable		 5d4uC-2cq4A:
16.60