SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cqc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2cqc ARGININE/SERINE-RICH
SPLICING FACTOR 10
(Homo
sapiens) 		5 / 8 ALA A 175
GLU A 174
LEU A 120
ILE A 144
ILE A 149
 None
 1.35A 2uxpA-2cqcA:
undetectable		 2uxpA-2cqcA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2cqc ARGININE/SERINE-RICH
SPLICING FACTOR 10
(Homo
sapiens) 		5 / 11 ALA A 175
GLU A 174
VAL A 122
GLY A 142
ILE A 144
 None
 1.27A 2uxpB-2cqcA:
undetectable		 2uxpB-2cqcA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2cqc ARGININE/SERINE-RICH
SPLICING FACTOR 10
(Homo
sapiens) 		3 / 3 TYR A 128
ARG A 187
SER A 126
 None
 1.09A 4lf7I-2cqcA:
undetectable
4lf7J-2cqcA:
undetectable		 4lf7I-2cqcA:
20.49
4lf7J-2cqcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2cqc ARGININE/SERINE-RICH
SPLICING FACTOR 10
(Homo
sapiens) 		3 / 3 TYR A 128
ARG A 187
SER A 126
 None
 1.09A 4lf8I-2cqcA:
undetectable
4lf8J-2cqcA:
undetectable		 4lf8I-2cqcA:
20.49
4lf8J-2cqcA:
19.64