SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_A_EAAA223_1 (GLUTATHIONE TRANSFERASE A1-1)	2cqk	C-MPL BINDING PROTEIN (Homo sapiens)	4 / 8	GLY A 119 LEU A 104 VAL A 87 PHE A 81	None	1.21A	1gsfA-2cqkA: undetectable	1gsfA-2cqkA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_B_EAAB223_1 (GLUTATHIONE TRANSFERASE A1-1)	2cqk	C-MPL BINDING PROTEIN (Homo sapiens)	4 / 8	GLY A 119 LEU A 104 VAL A 87 PHE A 81	None	1.21A	1gsfB-2cqkA: undetectable	1gsfB-2cqkA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_D_EAAD223_1 (GLUTATHIONE TRANSFERASE A1-1)	2cqk	C-MPL BINDING PROTEIN (Homo sapiens)	4 / 8	GLY A 119 LEU A 104 VAL A 87 PHE A 81	None	1.21A	1gsfD-2cqkA: undetectable	1gsfD-2cqkA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	2cqk	C-MPL BINDING PROTEIN (Homo sapiens)	4 / 5	VAL A 115 GLY A 119 VAL A 122 TRP A 85	None	1.28A	1tkqB-2cqkA: undetectable	1tkqB-2cqkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_A_ZMRA1776_2 (NEURAMINIDASE A)	2cqk	C-MPL BINDING PROTEIN (Homo sapiens)	4 / 6	ASP A 99 ILE A 103 LEU A 53 GLU A 105	None	1.03A	2ya7A-2cqkA: undetectable	2ya7A-2cqkA: 10.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GSF_A_EAAA223_1","GLUTATHIONE TRANSFERASE A1-1","2cqk","C-MPL BINDING PROTEIN","Homo sapiens",4,"GLY A 119;LEU A 104;VAL A  87;PHE A  81","None","1.21A","1gsfA-2cqkA:undetectable","1gsfA-2cqkA:19.80"],["1GSF_B_EAAB223_1","GLUTATHIONE TRANSFERASE A1-1","2cqk","C-MPL BINDING PROTEIN","Homo sapiens",4,"GLY A 119;LEU A 104;VAL A  87;PHE A  81","None","1.21A","1gsfB-2cqkA:undetectable","1gsfB-2cqkA:19.80"],["1GSF_D_EAAD223_1","GLUTATHIONE TRANSFERASE A1-1","2cqk","C-MPL BINDING PROTEIN","Homo sapiens",4,"GLY A 119;LEU A 104;VAL A  87;PHE A  81","None","1.21A","1gsfD-2cqkA:undetectable","1gsfD-2cqkA:19.80"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","2cqk","C-MPL BINDING PROTEIN","Homo sapiens",4,"VAL A 115;GLY A 119;VAL A 122;TRP A  85","None","1.28A","1tkqB-2cqkA:undetectable","1tkqB-2cqkA:10.00"],["2YA7_A_ZMRA1776_2","NEURAMINIDASE A","2cqk","C-MPL BINDING PROTEIN","Homo sapiens",4,"ASP A  99;ILE A 103;LEU A  53;GLU A 105","None","1.03A","2ya7A-2cqkA:undetectable","2ya7A-2cqkA:10.95"]]