SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J78_B_VDYB500_1
(VITAMIN D BINDING
PROTEIN)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		5 / 10 VAL A  19
TYR A  78
LYS A  43
LEU A  65
SER A  51
 None
 1.35A 1j78B-2cqvA:
undetectable		 1j78B-2cqvA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.70A 1usqA-2cqvA:
undetectable		 1usqA-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.71A 1usqB-2cqvA:
undetectable		 1usqB-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.70A 1usqC-2cqvA:
undetectable		 1usqC-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.72A 1usqD-2cqvA:
undetectable		 1usqD-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.72A 1usqE-2cqvA:
undetectable		 1usqE-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.69A 1usqF-2cqvA:
undetectable		 1usqF-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		5 / 11 GLY A 110
SER A 113
ASP A 102
THR A 107
GLY A 106
 None
 0.96A 2hmaA-2cqvA:
undetectable		 2hmaA-2cqvA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.78A 2jkjA-2cqvA:
undetectable		 2jkjA-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.77A 2jkjB-2cqvA:
undetectable		 2jkjB-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.78A 2jkjC-2cqvA:
undetectable		 2jkjC-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.77A 2jkjE-2cqvA:
undetectable		 2jkjE-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.76A 2jklA-2cqvA:
undetectable		 2jklA-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 6 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.78A 2jklB-2cqvA:
undetectable		 2jklB-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.78A 2jklD-2cqvA:
undetectable		 2jklD-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.77A 2jklE-2cqvA:
undetectable		 2jklE-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES
(Homo
sapiens) 		4 / 7 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.77A 2jklF-2cqvA:
undetectable		 2jklF-2cqvA:
22.15