SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cr3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2cr3 BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		5 / 12 ALA A  70
VAL A  41
GLY A  40
ASN A  35
VAL A  72
 None
 1.20A 3f8wA-2cr3A:
undetectable		 3f8wA-2cr3A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2cr3 BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		4 / 8 ASP A  60
GLY A  18
VAL A  86
ARG A  24
 None
 0.67A 4acbB-2cr3A:
undetectable
4acbC-2cr3A:
undetectable		 4acbB-2cr3A:
12.17
4acbC-2cr3A:
12.17