SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2crf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JFA_A_RALA600_2 (ESTROGEN RECEPTOR)	2crf	RAN BINDING PROTEIN 3 (Homo sapiens)	4 / 5	LEU A 67 ASP A 64 LEU A 56 HIS A 134	None	0.97A	2jfaA-2crfA: undetectable	2jfaA-2crfA: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A131_2 (FATTY ACID-BINDING PROTEIN, LIVER)	2crf	RAN BINDING PROTEIN 3 (Homo sapiens)	4 / 6	LEU A 36 ASN A 57 ILE A 103 PHE A 116	None	1.21A	2jn3A-2crfA: undetectable	2jn3A-2crfA: 23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_A_RALA600_2 (ESTROGEN RECEPTOR)	2crf	RAN BINDING PROTEIN 3 (Homo sapiens)	4 / 5	LEU A 67 ASP A 64 LEU A 56 HIS A 134	None	1.00A	2qxsA-2crfA: undetectable	2qxsA-2crfA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_B_RALB600_2 (ESTROGEN RECEPTOR)	2crf	RAN BINDING PROTEIN 3 (Homo sapiens)	4 / 5	LEU A 67 ASP A 64 LEU A 56 HIS A 134	None	1.00A	2qxsB-2crfA: undetectable	2qxsB-2crfA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	2crf	RAN BINDING PROTEIN 3 (Homo sapiens)	4 / 6	ILE A 82 ARG A 80 ARG A 49 VAL A 47	None	1.36A	4mk4B-2crfA: undetectable	4mk4B-2crfA: 17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTW_A_DB8A1101_2 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	2crf	RAN BINDING PROTEIN 3 (Homo sapiens)	3 / 3	LEU A 56 LEU A 36 ASN A 84	None	0.73A	4otwA-2crfA: undetectable	4otwA-2crfA: 21.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2JFA_A_RALA600_2","ESTROGEN RECEPTOR","2crf","RAN BINDING PROTEIN 3","Homo sapiens",4,"LEU A  67;ASP A  64;LEU A  56;HIS A 134","None","0.97A","2jfaA-2crfA:undetectable","2jfaA-2crfA:22.98"],["2JN3_A_JN3A131_2","FATTY ACID-BINDING PROTEIN, LIVER","2crf","RAN BINDING PROTEIN 3","Homo sapiens",4,"LEU A  36;ASN A  57;ILE A 103;PHE A 116","None","1.21A","2jn3A-2crfA:undetectable","2jn3A-2crfA:23.57"],["2QXS_A_RALA600_2","ESTROGEN RECEPTOR","2crf","RAN BINDING PROTEIN 3","Homo sapiens",4,"LEU A  67;ASP A  64;LEU A  56;HIS A 134","None","1.00A","2qxsA-2crfA:undetectable","2qxsA-2crfA:20.77"],["2QXS_B_RALB600_2","ESTROGEN RECEPTOR","2crf","RAN BINDING PROTEIN 3","Homo sapiens",4,"LEU A  67;ASP A  64;LEU A  56;HIS A 134","None","1.00A","2qxsB-2crfA:undetectable","2qxsB-2crfA:20.77"],["4MK4_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","2crf","RAN BINDING PROTEIN 3","Homo sapiens",4,"ILE A  82;ARG A  80;ARG A  49;VAL A  47","None","1.36A","4mk4B-2crfA:undetectable","4mk4B-2crfA:17.61"],["4OTW_A_DB8A1101_2","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3","2crf","RAN BINDING PROTEIN 3","Homo sapiens",3,"LEU A  56;LEU A  36;ASN A  84","None","0.73A","4otwA-2crfA:undetectable","4otwA-2crfA:21.74"]]