SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2cri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9K_B_CAMB424_0 (CYTOCHROME P450)	2cri	VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A (Mus musculus)	5 / 9	THR A 35 LEU A 126 LEU A 23 VAL A 61 VAL A 78	None	1.48A	4c9kB-2criA: undetectable	4c9kB-2criA: 16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA502_0 (RNA POLYMERASE 3D-POL)	2cri	VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A (Mus musculus)	3 / 3	ARG A 127 LYS A 125 LYS A 94	None	1.30A	4k50A-2criA: undetectable	4k50A-2criA: 17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE502_0 (RNA POLYMERASE 3D-POL)	2cri	VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A (Mus musculus)	3 / 3	ARG A 127 LYS A 125 LYS A 94	None	1.25A	4k50E-2criA: undetectable	4k50E-2criA: 17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI506_0 (RNA POLYMERASE 3D-POL)	2cri	VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A (Mus musculus)	3 / 3	ARG A 127 LYS A 125 LYS A 94	None	1.26A	4k50I-2criA: undetectable	4k50I-2criA: 17.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4C9K_B_CAMB424_0","CYTOCHROME P450","2cri","VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A","Mus musculus",5,"THR A  35;LEU A 126;LEU A  23;VAL A  61;VAL A  78","None","1.48A","4c9kB-2criA:undetectable","4c9kB-2criA:16.15"],["4K50_A_ACTA502_0","RNA POLYMERASE 3D-POL","2cri","VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A","Mus musculus",3,"ARG A 127;LYS A 125;LYS A  94","None","1.30A","4k50A-2criA:undetectable","4k50A-2criA:17.69"],["4K50_E_ACTE502_0","RNA POLYMERASE 3D-POL","2cri","VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A","Mus musculus",3,"ARG A 127;LYS A 125;LYS A  94","None","1.25A","4k50E-2criA:undetectable","4k50E-2criA:17.69"],["4K50_I_ACTI506_0","RNA POLYMERASE 3D-POL","2cri","VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A","Mus musculus",3,"ARG A 127;LYS A 125;LYS A  94","None","1.26A","4k50I-2criA:undetectable","4k50I-2criA:17.69"]]