SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2crn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		5 / 12 THR A  37
THR A  33
ALA A  32
ALA A  43
HIS A  48
 None
 1.17A 3mg02-2crnA:
undetectable
3mg0V-2crnA:
undetectable		 3mg02-2crnA:
15.88
3mg0V-2crnA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		5 / 11 MET A  19
PHE A  21
LEU A  12
THR A  33
ALA A  32
 None
 1.30A 4dx7A-2crnA:
undetectable		 4dx7A-2crnA:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		5 / 12 HIS A  48
THR A  37
THR A  33
ALA A  32
ALA A  43
 None
 1.09A 4qvnV-2crnA:
undetectable
4qvnb-2crnA:
undetectable		 4qvnV-2crnA:
15.20
4qvnb-2crnA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		5 / 12 HIS A  48
THR A  37
THR A  33
ALA A  32
ALA A  43
 None
 1.09A 4qvnH-2crnA:
undetectable
4qvnN-2crnA:
undetectable		 4qvnH-2crnA:
15.20
4qvnN-2crnA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		3 / 3 LEU A  30
ALA A  29
LEU A  13
 None
 0.51A 5uunB-2crnA:
undetectable		 5uunB-2crnA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		5 / 12 HIS A  48
THR A  37
THR A  33
ALA A  32
ALA A  43
 None
 1.10A 6hwdV-2crnA:
undetectable
6hwdb-2crnA:
undetectable		 6hwdV-2crnA:
21.05
6hwdb-2crnA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 2crn UBASH3A PROTEIN
(Homo
sapiens) 		5 / 12 HIS A  48
THR A  37
THR A  33
ALA A  32
ALA A  43
 None
 1.10A 6hwdH-2crnA:
undetectable
6hwdN-2crnA:
undetectable		 6hwdH-2crnA:
21.05
6hwdN-2crnA:
16.67