SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2crp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_2 (RETINOIC ACID RECEPTOR, BETA)	2crp	REGULATOR OF G-PROTEIN SIGNALING 5 (Homo sapiens)	3 / 3	LEU A 32 PHE A 42 ARG A 121	None	0.81A	1xdkB-2crpA: undetectable	1xdkB-2crpA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_2 (RETINOIC ACID RECEPTOR, BETA)	2crp	REGULATOR OF G-PROTEIN SIGNALING 5 (Homo sapiens)	3 / 3	LEU A 32 PHE A 42 ARG A 121	None	0.81A	1xdkF-2crpA: undetectable	1xdkF-2crpA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA504_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	2crp	REGULATOR OF G-PROTEIN SIGNALING 5 (Homo sapiens)	4 / 8	ILE A 85 ILE A 95 THR A 99 THR A 103	None	0.65A	4em2A-2crpA: undetectable	4em2A-2crpA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K38_B_SAMB504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	2crp	REGULATOR OF G-PROTEIN SIGNALING 5 (Homo sapiens)	5 / 12	CYH A 61 GLU A 83 GLN A 79 ILE A 67 LEU A 112	None	1.16A	4k38B-2crpA: undetectable	4k38B-2crpA: 17.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XDK_B_9CRB600_2","RETINOIC ACID RECEPTOR, BETA","2crp","REGULATOR OF G-PROTEIN SIGNALING 5","Homo sapiens",3,"LEU A  32;PHE A  42;ARG A 121","None","0.81A","1xdkB-2crpA:undetectable","1xdkB-2crpA:20.27"],["1XDK_F_9CRF1600_2","RETINOIC ACID RECEPTOR, BETA","2crp","REGULATOR OF G-PROTEIN SIGNALING 5","Homo sapiens",3,"LEU A  32;PHE A  42;ARG A 121","None","0.81A","1xdkF-2crpA:undetectable","1xdkF-2crpA:20.27"],["4EM2_A_SALA504_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","2crp","REGULATOR OF G-PROTEIN SIGNALING 5","Homo sapiens",4,"ILE A  85;ILE A  95;THR A  99;THR A 103","None","0.65A","4em2A-2crpA:undetectable","4em2A-2crpA:21.21"],["4K38_B_SAMB504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","2crp","REGULATOR OF G-PROTEIN SIGNALING 5","Homo sapiens",5,"CYH A  61;GLU A  83;GLN A  79;ILE A  67;LEU A 112","None","1.16A","4k38B-2crpA:undetectable","4k38B-2crpA:17.34"]]